On July 28, 2021 Zion Pharma of Hong Kong reported that it raised $40 million in a Series B financing led by OrbiMed to advance its small molecule cancer drugs (Press release, Zion Pharma, JUL 28, 2021, View Source [SID1234585445]). Founded in 2018, Zion is based on its expertise in DMPK that allows the company to develop drugs capable of crossing the blood-brain barrier. The company’s lead product in a tyrosine kinase receptor inhibitor targeting HER2 aimed at treating brain metastases accompanying HER2+ breast cancer. The candidate, ZN-A-104, has completed China and US initial trials. Zion is headquartered in Hong Kong with research operations in Shanghai and Suzhou.

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