Xylyx Bio and Cell&Soft Announce positive initial results following Strategic Partnership to Develop Next-Generation in vitro Platforms to Accelerate Cancer Drug Discovery

On February 2, 2021 Xylyx Bio, a leader in predictive disease models and tissue-specific extracellular matrix (ECM) products, and Cell&Soft SAS, a French biotech company specializing in innovative soft cell culture plates, reported positive preliminary results, reaching a key milestone in their partnership to develop more physiologically relevant in vitro cellular models for cell-based assays in oncology (Press release, Xylyx Bio, FEB 2, 2021, View Source [SID1234574517]).

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Existing in vitro models lack physiological relevance, yielding misleading and non-translatable results that slow essential progress needed to develop effective drugs capable of preventing thousands of cancer deaths each year.

The collaboration initially focuses on the development of products for lung adenocarcinoma. The promising early results indicated that the combination of Xylyx Bio lung-specific ECM surface coatings and Cell&Soft soft cell culture plates are compatible technologies and that lung tumor cells are highly functional in this environment. The resulting lung-specific soft cell culture products will enable scientists to develop more physiologically relevant pre-clinical tumor models to substantially improve the identification and selection of effective lung cancer therapies.

Camille Migdal, Ph.D., President and Co-Founder of Cell&Soft, said, "We are excited about combining our soft cell culture plates mimicking lung rigidity with Xylyx Bio lung-specific extracellular matrix. It opens a way towards innovative and relevant products for pulmonary in vitro cell culture."

Andrea Nye, President & CEO of Xylyx Bio, explained, "Collaborative relationships with innovative companies like Cell&Soft support the creation of improved tools that enable researchers to better model disease biology and increase predictability of drug efficacy, helping shift the overall paradigm from entrenched, non-predictive in vitro models to more accurate and actionable drug discovery."