On August 25, 2023 Novartis Pharma AG ("Novartis") reported to XOMA Corporation (the "Company" or "XOMA") that it intends to discontinue development activities related to NIS793, an anti-TGFß monoclonal antibody (Press release, Xoma, AUG 25, 2023, View Source [SID1234634698]). Novartis will cease enrolling patients in the remaining active TGFß clinical studies and will collect all data upon conclusion of these studies.
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XOMA licensed NIS793 to Novartis pursuant to that certain License Agreement, dated as of September 30, 2015, by and between XOMA (US) LLC, a wholly owned subsidiary of the Company, and Novartis Institutes for Biomedical Research, Inc., previously filed with the Securities and Exchange Commission as Exhibit 10.2 to its Quarterly Report on Form 10-Q for the period ended September 30, 2015.
NIS793 is an investigational compound. Efficacy and safety have not been established. There is no guarantee that NIS793 will become commercially available.