Sirnaomics to Present Latest Developments on Two Proprietary Delivery Platforms at Upcoming Industry Conferences

On July 12, 2023 Sirnaomics Ltd. (the "Company", stock code: 2257, together with its subsidiaries, the "Group" or "Sirnaomics"), a leading biopharmaceutical company engaging in discovery and development of advanced RNAi therapeutics, hereby reported that Sirnaomics’ Senior Director of Technology Innovation, Dr. Weterings will present the latest developments on its of GalAhead, GalNAc-RNAi therapeutic platforms and related pipeline programs at international industry conferences taking place in July (Press release, Sirnaomics, JUL 12, 2023, View Source [SID1234633202]). Sirnaomics’ Vice President of Chemistry, Manufacturing, and Controls processes, Dr. Welch will present the Polypeptide Nanoparticle platform’s technology, at international industry conferences taking place in August.

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9th Annual Drug Delivery Systems Presentation Details

Presentation Title: GalAhead: A Proprietary GalNAc-RNAi Therapeutic Platform to Downregulate Single and Multiple Genes
Presenter: Jim Weterings, Ph.D., Sirnaomics Senior Director of Technology Innovation
Time/Date: 1:35 pm CEST on Wednesday, July 12, 2023
Location: Holiday Inn Amsterdam Arena Towers, the Netherlands
Presentation content:
Introduction to GalAhead, Sirnaomics’ GalNAc-RNAi therapeutic platform
Validation of technology in vivo and in vitro
Progress report on GalAhead-based programs
2nd Annual Oligonucleotides CMC & Analytical Development Summit Presentation Details

Presentation Title: Challenges for Development, Scale Up & Production of Novel Oligonucleotide
Presenter: Richard Welch, Ph.D., Sirnaomics Vice President of Chemistry, Manufacturing & Controls
Time/Date: 12:15 pm ET on Wednesday, Aug. 30, 2023
Location: Boston, MA
Presentation Content:
Unique supply chain requirement challenges
Sourcing of CDMO support
Evaluating multiple regulatory challenges faced in a global production environment

Panel Discussion: Scaling Up & Meeting Oligonucleotide Demand
Time: 11:30 am
Panel Content:
Moving into non-rare disease areas and producing oligonucleotides at scale for larger populations
Evaluating technologies and the advantages and limitations of scale
Analytical readiness for process change and late phase: strategic, regulatory, and technical perspectives