On May 7, 2020 Sierra Oncology, Inc. (SRRA), a late-stage drug development company focused on the registration and commercialization of momelotinib, a JAK1, JAK2 & ACVR1 inhibitor with a potentially differentiated therapeutic profile for the treatment of myelofibrosis, reported that it will host an Analyst & Investor Call to discuss anemia and transfusion dependency, two critical unmet medical needs in treating patients with myelofibrosis, on Wednesday, May 13th at 10:00 am ET (Press release, Sierra Oncology, MAY 7, 2020, View Source [SID1234557322]). The event will feature a presentation by renowned myelofibrosis expert Dr. Ruben Mesa, Director of the Mays Cancer Center, home to UT Health San Antonio MD Anderson Cancer Center.
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"Cytopenias are very common in myelofibrosis, with anemia and the resulting transfusion dependency being strongly associated with poor prognosis and impaired survival in this disease," said Dr. Mesa. "In clinical trials, momelotinib has consistently demonstrated immediate and sustained anemia benefits that manifest in an overall reduced transfusion burden, while sparing platelets and achieving clinically comparable benefits on symptoms and splenomegaly to that of the standard-of-care agent, ruxolitinib. With treatments desperately lacking both for first line patients with either severe anemia or transfusion dependency at presentation, and for the largely cytopenic second line population, momelotinib may offer a potentially important and broadly used new therapeutic option for patients. As such advancing the MOMENTUM Phase 3 trial, which is currently enrolling patients, is a high priority for the MF clinical community."
Dr. Mesa’s practice builds on his role as an international expert on myeloproliferative neoplasms (MPNs), a group of bone marrow disorders which include myelofibrosis. He has been involved in MPN research for more than 20 years. He led the development of National Comprehensive Cancer Network’s panel guidelines, the first U.S. guidelines on the diagnosis and treatment of myelofibrosis, polycythemia vera and essential thrombocythemia. Dr. Mesa was elected to sit on the National Board of Directors for the Leukemia and Lymphoma Society and sits on the board of the MPN Education Foundation. Dr. Mesa is an investigator in the MOMENTUM Phase 3 trial of momelotinib, which is intended to confirm the array of clinical benefits previously described for the drug candidate.
Dr. Mesa and members of Sierra Oncology’s senior management team will be available to answer questions from analysts at the conclusion of the event.
Analyst and Investor Event and Webcast Information
Date and Time: Wednesday, May 13th at 10:00 am ET
Domestic (Toll Free- US): 1-877-407-4018
International (Toll): 1-201-689-8471
Conference ID: 13702348
Webcast Link: View Source;tp_key=8595ee9eeb
Call registration is available through the Sierra Oncology website at www.sierraoncology.com. An archive of the presentation will be accessible after the event through the Sierra Oncology website.