On January 19, 2022 RenovoRx, Inc. ("RenovoRx" or the "Company") (Nasdaq: RNXT), a biopharmaceutical company and innovator in targeted cancer therapy, reported that Dr. Ripal Gandhi, M.D., FSIR, FSVM, a Principal Investigator in the Company’s Phase 3 TIGeR-PaC study, presented ‘Trans-arterial Treatment Option in Pancreas Cancer’ at the recent 2022 SPECTRUM Conference (Press release, Renovorx, 19 19, 2022, View Source [SID1234605660]). Dr. Gandhi is professor of Interventional Radiology at the Miami Cancer Institute and Miami Cardiac and Vascular Institute, Florida International University Herbert Wertheim College of Medicine. The 2022 SPECTRUM conference was held last weekend, January 14-16, 2022, at the Nobu Hotel in Miami Beach, Florida.
Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:
Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing
Schedule Your 30 min Free Demo!
Since 2018, Dr. Gandhi has played a pivotal role in the TIGeR-PaC clinical trial as the PI for the Miami Cancer Institute. The TIGeR-PaC study is evaluating the Company’s novel therapy platform, RenovoTAMP (RenovoRx Trans-Arterial Micro-Perfusion) as a potential treatment option for locally advanced pancreatic cancer (LAPC) that may extend patient survival, reduce the typical, often debilitating side-effects associated with systemic chemotherapy (delivered intra-venously), and ultimately improve quality of life for pancreatic cancer patients.
Dr. Gandhi’s presentation at the 2022 SPECTRUM Conference provides an overview of the RenovoTAMP platform and supportive published research. The presentation showcased RenovoRx’s RR1 Phase I/II and RR2 Observational Registry studies that suggests that when RenovoTAMP is used in combination with radiation therapy, arterial microvasculature may be reduced, thereby minimizing chemotherapy leakage during delivery, and increasing the chemotherapy directly reaching the tumor – resulting in targeted delivery and reduced systemic side effects. In addition, Dr. Gandhi also shared preliminary pharmacokinetic data (data describing the absorption, distribution, metabolism, and excretion of chemotherapy) from five patients in the TIGeR-PaC study, which demonstrates an approximate two-thirds reduction in systemic gemcitabine, when compared to systemic levels in historical control patients receiving traditional IV infusion of gemcitabine. This data suggests that by using RenovoTAMP for targeted delivery of chemotherapy, the systemic impacts of chemotherapy may be being reduced.
"We appreciate Dr. Gandhi, a recognized expert specializing in minimally invasive treatments for cancer, both in his role as a Principal Investigator for the TIGeR-PaC study supporting our patients and their families, and for his ongoing efforts to educate clinicians throughout the medical community on the potential for RenovoTAMP as an option for the treatment of their patients with LAPC, " stated Dr. Ramtin Agah, Chief Medical Officer and Co-Founder of RenovoRx. He continued, "Our foundational studies provided support for the potential for intra-arterial delivery via RenovoTAMP to improve patient survival and counter the tolerability issues inherent to chemotherapy, which improves quality of life for patients during this critical time. Our team continues to make progress enrolling our Phase 3 clinical trial and looks forward to reporting on the interim data read out."
View Dr. Gandhi’s presentation, titled "Trans-arterial Treatment Option in Pancreas Cancer," at View Source
About the 2022 SPECTRUM Conference
The SPECTRUM conference offers attendees a comprehensive review of a variety of oncological diseases, combined with the latest developments in medical, interventional and surgical therapeutic options across multiple disciplines. SPECTRUM is both didactic and interactive with panel discussions, instructive case presentations and hands-on workshops focused on hepatocellular carcinoma, lung cancer, metastatic colorectal cancer, cholangiocarcinoma and liver metastases, renal and prostate cancer, pancreatic cancer, neuroendocrine and musculoskeletal tumors.