Prokarium expands IP portfolio with two new U.S. patents strengthening its position in bladder cancer

On November 1, 2024 Prokarium, a biopharmaceutical company developing innovative cancer treatments, reported the receipt of two Notices of Allowance from the United States Patent and Trademark Office (USPTO) (Press release, Prokarium, NOV 1, 2024, View Source [SID1234647637]). These patents, covering applications Nos. 17/752,707 and 18/559,543, strengthen Prokarium’s mission to develop innovative, scalable therapies that address critical gaps in cancer treatment.

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Application No. 17/752,707 protects the co-administration of Prokarium’s proprietary Salmonella strains with immune checkpoint inhibitors to enhance the checkpoint inhibitors therapeutic efficacy. "This patent, alongside our granted patent in combination with cell therapies, is a significant step toward scaling our technology’s potential in the oncology space," said Dr. Livija Deban, CSO at Prokarium. "By advancing our technology to amplify the effects of immune checkpoint inhibitors, we’re demonstrating a value proposition that investors and partners can rely on as we work towards scalable, impactful cancer treatments."

Application No. 18/559,543 protects an advanced Salmonella-based method for treating neoplastic diseases by promoting a robust immune response along with targeted anti-tumor action. "This patent bolsters our IP portfolio and, more importantly, creates a stronger foundation for our clinical program in bladder cancer," said Kristen Albright, PharmD, Chief Executive Officer at Prokarium. "Together, these innovations represent a major value driver for the company, strengthening our position to attract strategic partners and investors as we address large, underserved markets in cancer immunotherapy."