On November 16, 2022 Precision Biologics, Inc. ("Precision"), a clinical-stage immunotherapy and targeted oncology company, reported that it will present at the SITC (Free SITC Whitepaper) 37th Annual Meeting (2022) in Boston, MA (Press release, Precigen, NOV 16, 2022, View Source [SID1234623581]).
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The first poster presentation will discuss the novel target for its NEO-201 monoclonal antibody and mechanism of action for this drug including the specific O-glycan epitope recognized by NEO-201 and that NEO-201 kills target cells expressing core 1 and/or extended core 1 O-glycans through Antibody-Dependent Cellular Cytotoxicity (ADCC)
The second poster presentation will discuss the ongoing Phase 2 clinical trial being conducted at the National Cancer Institute that combines NEO-201 with Pembrolizumab in patients with treatment refractory solid tumors. The study is enrolling patients at the National Cancer Institute, Bethesda, MD, with metastatic Non-Small Cell Lung Cancer (NSCLC), Head and Neck Cancers, Endometrial Cancer and Cervical Cancer, who have already been treated with checkpoint inhibitor therapy (including prior Keytruda). (View Source)
Posters will be presented in person at the at the Boston Convention and Exhibition Center on Thursday November 10th, 2022.