On May 24, 2022 PanTher Therapeutics (PanTher), a clinical-stage oncology company developing next-generation targeted therapies for solid tumors, reported that a methods-of-use patent for a deployable anticancer drug-eluting stent, exclusively licensed to PanTher, has been issued by the United States Patent and Trademark Office (USPTO) (Press release, PanTher Therapeutics, MAY 24, 2022, View Source [SID1234614997]). The patent increases the potential applicability of PanTher’s proprietary Sagittari treatment platform, which focuses on direct, localized, and sustained delivery of proven and novel therapeutic agents to attack cancer at the source.
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The newly awarded patent covers methods of treating a tumor using a drug-eluting stent that incorporates a degradable polymer film containing a chemotherapeutic drug. The drug is released from the film when the stent is deployed into a biliary or pancreatic duct or tissue site of the pancreas, biliary system, gallbladder, liver, small bowel, or colon.
"The patent validates the novelty and breadth of the Sagittari platform and increases our potential market, while enhancing the value of our intellectual property portfolio," said Laura Indolfi, PhD, chief executive officer of PanTher Therapeutics. "It also supports our investigational strategy of applying our technology to multiple solid tumor types, which facilitates the selection of our follow-on assets."
The Sagittari️ platform is an optimized system for precisely transporting therapeutics to the tumor site, leveraging interventional oncology to design superior localized cancer treatments. PanTher’s lead candidate, PTM-101, the first product to emerge from the Sagittari platform, is currently in Phase 1 of clinical development for the treatment of localized non-metastatic pancreatic cancers.
PanTher also announced the appointment of Dan Wildman as a strategic advisor to the company. A seasoned executive with more than 35 years of experience in the MedTech industry, Mr. Wildman is president and chief executive officer of the strategic consulting company Wildman Ventures, LLC. He previously led the Digital Surgery Strategy initiative at Johnson & Johnson and served as worldwide president of Depuy Synthes Spine and Ethicon Biosurgery. While at Ethicon Biosurgery, Mr. Wildman led the development and commercialization of a novel combination product based on a biomaterial and biologic formulation. As strategic advisor to PanTher, Mr. Wildman will apply this expertise and his decades of experience to advancing the clinical development program for PTM-101 and selecting and prioritizing other Sagittari platform product candidates.
"I am excited to join PanTher at such a pivotal moment in the company’s trajectory, with its first asset in the clinic and a newly issued patent that positions the company very competitively in a crowded space," commented Mr. Wildman. "I look forward to contributing to the growth and expansion of the company and helping realize the tremendous market potential of its pipeline."