On May 1, 2020 OrigiMed (Shanghai), a precision medicine company, reported a collaboration with Germany’s Bayer to develop a China in vitro companion diagnostic (CDx-IVD) to detect NTRK gene fusions (Press release, ChinaBio, MAY 1, 2020, View Source [SID1234556913]). Bayer’s larotrectinib (Vitrakvi) is a TRK inhibitor approved in the US (2018) and EU (2019) to treat adult and pediatric patients with solid tumor TRK fusion cancers. Larotrectinib is being developed globally, including in China. OrigiMed uses high-throughput analysis together with bioinformatics and clinical data to match patients with targeted therapies, immunotherapies and clinical trials.
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