On March 3, 2021 Oasmia Pharmaceutical AB, an innovation-focused specialty pharmaceutical company, reported that it has signed an agreement with the Karolinska Institutet, Stockholm, Sweden (Press release, Oasmia, MAR 3, 2021, View Source [SID1234575986]).
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The collaboration will generate new information aiming at the development of new therapeutic APIs. The XR-17 proprietary platform technology enhances intravenous delivery of established and novel drugs in diseases including cancer.
The collaboration will include a review of data and experimental methods to gain a deeper understanding of XR-17 and API formulations in cancer indications with a focus on ovarian carcinoma. This will be followed by an experimental planning phase, which aims to test formulations in suitable systems to generate hypotheses for subsequent evaluation.
Commenting on the collaboration, François Martelet, M.D., Chief Executive Officer of Oasmia, said: "XR-17’s potential to improve drug solubility has been demonstrated by the approval of Apealea for ovarian cancer in Europe, with a second investigational product preparing to enter clinical studies in Switzerland this year. We are delighted to be working with the Karolinska Institutet, one of the most prestigious medical universities and research centers in the world, to further develop our understanding of the potential of this technology in enhancing cancer treatment. Our collaboration with Prof. Rolf Lewensohn and his team at the Department of Oncology-Pathology may lead to the identification of additional applications for the technology and the development of new therapeutics to benefit cancer and other patients."
Prof. Rolf Lewensohn, Principal Investigator at the Karolinska Institutet, Department of Oncology-Pathology, said: "We are looking forward to working with Oasmia on this project. The knowledge and understanding we will be able to generate through this collaboration will help us to better understand the biological properties of XR-17 by defining plasma and target tissue behavior and receptor and transporter affinity. This important work could ultimately enable new study protocols to be drafted."