On April 10, 2025 Nona Biosciences, a global biotechnology company providing a total solution from "Idea to IND" (I to ITM), reported a research collaboration with Atossa Therapeutics Inc. (Nasdaq: ATOS) (Press release, Nona Biosciences, APR 10, 2025, View Source [SID1234651870]). The collaboration leverages Nona’s proprietary H2L2 Harbour Mice platform to identify next-generation therapeutic candidates for breast cancer.
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Nona Biosciences’ proprietary Harbour Mice platform employs transgenic mice to generate fully human monoclonal antibodies in both the conventional two heavy and two light chain (H2L2) format and the heavy chain-only (HCAb) format, eliminating the need for additional engineering or humanization. Combined with the single B cell cloning technology, this platform offers a powerful approach to developing therapeutic antibodies and accelerating drug discovery and development. To date, Harbour Mice platform has been applied in more than 250 drug discovery programs across multiple therapeutic areas and has been widely recognized by global partners
"We are pleased to collaborate with Atossa Therapeutics to discover next-generation antibody therapies for breast cancer," said Jingsong Wang, M.D., Ph.D., Chairman of Nona Biosciences. "This partership highlights the value of our proprietary Harbour Mice platform and reflects the industry’s growing demand for innovative antibody discovery solutions. With Nona’s industry-leading technology and expertise, we look forward to supporting Atossa’s exploration of antibody-based approaches within their oncology pipeline."