On November 1, 2023 NanoString Technologies, a leading provider of life sciences tools for discovery and translational research, reported the line-up of researchers joining NanoString at the 38th annual meeting of the Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper) to be held in San Diego, CA (Press release, NanoString Technologies, NOV 1, 2023, View Source [SID1234636683]).

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Dr. Aubrey Thompson of the Mayo Clinic and Amaya Pankaj, a research fellow from Dr. David Ting’s Lab at Massachusetts General Hospital, will share the first data from NanoString’s newest assay for the GeoMx Digital Spatial Profiler (DSP). The GeoMx Immuno-oncology Proteome Atlas (IPA) is the industry’s most comprehensive spatial proteomics panel, enabling unprecedented spatial profiling of more than 570+ relevant targets from FFPE (Formalin-Fixed, Paraffin-Embedded) tissue sections.

Dr. Thompson will share a comparison of early-stage HER2+ tumor biopsies from patients, both responders and non-responders to neoadjuvant treatment. "The ability to interrogate the abundance and spatial distribution of 570 proteins is little short of breathtaking," said Dr. Thompson. He added, "The initial data that we have generated using the IPA assay are very provocative, and we look forward to using these exciting new reagents to further explore the spatial biology of breast cancer."

The GeoMx IPA assay offers researchers more than five times the content of any competing panel, providing access to unparalleled information. Its utility is applicable to the search for novel biomarkers and drug targets, investigating therapeutic response, stratifying patients, and determining drug mechanisms of action.

NanoString will host a lunchtime symposium on Friday, November 3rd, entitled Revolutionizing Immuno-oncology with Spatial Biology. The workshop will feature a presentation by Ms. Pankaj from David Ting’s Lab on the dissection of pancreatic tumor cells by harnessing spatial multiomics using two NanoString products on the same slide, the GeoMx IPA for protein and the Whole Transcriptome Atlas for RNA. NanoString’s Chief Scientific Officer and SVP of R&D, Dr. Joseph Beechem, and Senior Director of Product Management, Vik Devgan, also will provide an overview of NanoString’s spatial biology solutions, applications and high-level product roadmap. The workshop will be held from 12:15 – 1:15 p.m. (PT) in room 16 AB.

With its partners Abcam and Visiopharm, NanoString will host an IPA happy hour from 5:00-7:00 p.m. also on November 3rd at its conference booth, number 213. Both partners will participate in all events and be available at NanoString’s booth during the conference to provide additional information.

"NanoString is honored to offer customers the unprecedented utility and power encapsulated in the new GeoMx IPA assay. We look forward to many opportunities during SITC (Free SITC Whitepaper) to discuss its transformative potential for researchers," said Brad Gray, President and CEO of NanoString.

The GeoMx IPA is available for pre-order now and will commence shipment in November 2023.