On November 3, 2016 MorphoSys AG (FSE: MOR; Prime Standard Segment; TecDAX, OTC: MPSYY) reported upcoming presentations of data on the Company’s proprietary hemato-oncological programs MOR208 and MOR202 at the 58th American Society of Hematology (ASH) (Free ASH Whitepaper) Annual Meeting, being held December 3-6, 2016 in San Diego, California/USA (Press release, MorphoSys, NOV 3, 2016, View Source [SID1234516292]).
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"We are pleased that updated clinical trial results with our antibodies MOR208 and MOR202 in patients with B-cell malignancies and multiple myeloma, respectively, will be shown at the upcoming ASH (Free ASH Whitepaper) conference as oral presentations," commented Dr. Arndt Schottelius, Chief Development Officer of MorphoSys AG. "We expect this will further demonstrate the potential of our proprietary development candidates for patients suffering from those hemato-oncological malignancies that have a particularly high unmet medical need."
Abstracts from MorphoSys’s proprietary programs accepted for presentation at ASH (Free ASH Whitepaper) 2016:
Single-Agent MOR208 in Relapsed or Refractory (R-R) Non-Hodgkin’s Lymphoma (NHL): Results from Diffuse Large B-Cell Lymphoma (DLBCL) and Indolent NHL Subgroups of a Phase IIa Study
The oral presentation will include updated clinical results, in particular with respect to duration of responses, from a phase 2a MOR208 monotherapy trial in adult patients with relapsed/refractory NHL including DLBCL and iNHL.
Abstract #623
Session Name: 626. Aggressive Lymphoma (Diffuse Large B-Cell and Other Aggressive B-Cell Non-Hodgkin Lymphomas) – Results from Prospective Clinical Trials: Novel Agents
Session Date: Monday, December 5, 2016
Session Time: 7:00am-8:30am (PST) (4:00pm-5:30pm CET)
Presentation Time: 8:00am PST (5:00pm CET)
Room: San Diego Convention Center, Room 6B
A Phase I/IIa Study of the CD38 Antibody MOR202 Alone and in Combination with Pomalidomide or Lenalidomide in Patients with Relapsed or Refractory Multiple Myeloma
The oral presentation will include updated safety and efficacy results from the ongoing phase 1/2a MOR202 dose-escalation study in pre-treated multiple myeloma patients. Results will in particular include maturing data from the MOR202 8mg/kg patient cohorts in combination with lenalidomide and pomalidomide as well as first results from the highest dose cohorts of 16mg/kg MOR202 in combination with lenalidomide and pomalidomide.
Abstract #1152
Session Name: 653. Myeloma: Therapy, excluding Transplantation: Immunotherapy
Session Date: Monday, December 5, 2016
Session Time: 4:30pm-6:00pm (PST) (December 6, 2016, 1:30am-3:00am CET)
Presentation Time: 5:45pm (PST) (December 6, 2016, 2:45am CET)
Room: San Diego Convention Center, Hall AB
Updated Results from a Phase II Study of the Fc Engineered CD19 Antibody MOR208 in Combination with Lenalidomide for Patients with Chronic Lymphocytic Leukemia (CLL) and Richter’s Transformation or Ibrutinib for Patients with Ibrutinib-Resistant Clones
The poster presentation will include safety and efficacy results from the ongoing phase 2 investigator initiated trial (IIT) of MOR208 in combination with lenalidomide or ibrutinib in CLL.
Abstract #4386
Session Name: 642. CLL: Therapy, excluding Transplantation: Poster III
Date: Monday, December 5, 2016
Presentation Time: 6:00pm-8:00pm (PST) (December 6, 2016, 3:00am-5:00am CET)
Location: San Diego Convention Center, Hall GH
In addition to the presentations, all abstracts will be published online in the December 1, 2016 supplemental volume of Blood.
Additional information can be found at www.hematology.org, including the abstracts.