MARKER THERAPEUTICS TO PRESENT FOUR POSTERS ON ITS T CELL-BASED IMMUNOTHERAPIES AT THE 2022 INTERNATIONAL SOCIETY FOR CELL & GENE THERAPY ANNUAL MEETING

On May 4, 2022 Marker Therapeutics, Inc. (Nasdaq: MRKR), a clinical-stage immuno-oncology company specializing in the development of next-generation T cell-based immunotherapies for the treatment of hematological malignancies and solid tumor indications, reported that the Company will present four posters on its Multi-Tumor-Associated Antigen (MultiTAA)-specific T cell therapies at the 2022 International Society for Cell & Gene Therapy (ISCT) Annual Meeting, being held May 4-7, 2022, in San Francisco (Press release, Marker Therapeutics, MAY 4, 2022, View Source [SID1234613559]).

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"We are excited to present data on our state-of-the-art T cell therapy manufacturing process for our MultiTAA-specific T cell product candidates at ISCT, including improvements resulting in faster manufacturing time and increased potency for our lead product candidate, MT-401, currently in a Phase 2 study for the treatment of post-transplant AML," said Peter L. Hoang, President & CEO of Marker Therapeutics. "We look forward to sharing additional details on our improved manufacturing process, which we believe has the potential to enhance clinical responses in patients. In addition, we will present more detail on the clinical results from the six-patient safety lead-in stage of our Phase 2 AML trial, previously reported in February 2022, which demonstrate that MT-401 was well-tolerated, eliminated measurable residual disease (MRD) in one MRD+ patient and induced epitope spreading."

The four posters will be presented on Thursday, May 5, from 5:45 p.m. – 7:15 p.m. PT.

MT-401 (multi-tumor associated antigen-specific T cells) utilized for treatment for MRD+ AML patients
Abstract #: 515
Presenter: Shukaib Arslan, MD, City of Hope Comprehensive Cancer Center
Long-term Characterization of T Cell Product Interactions using in vitro 3D tumor models and the Go-Rex Platform
Abstract #: 506
Presenter: Eric A. Smith, PhD, Marker Therapeutics
Rapid and Simplified Process for Manufacturing Multi-Tumor-Associated Antigen Specific T Cells
Abstract #: 936
Presenter: Anastasiya Smith, PhD, Marker Therapeutics
Automating Closed System Purification of White Blood Cells for T Cell Therapy Manufacturing
Abstract #: 937
Presenter: Anastasiya Smith, PhD, Marker Therapeutics
The posters will be available in the Publications section of Marker’s website at View Source at the beginning of the session.