On December 18, 2023 Manhattan BioSolutions, Inc. (Manhattan Bio or MABS), an emerging biotech company developing innovative precision biologics, reported its selection as an awardee of the Science in the City QuickFire Challenge launched by Johnson & Johnson Innovation LLC (Press release, Manhattan BioSolutions, DEC 18, 2023, View Source [SID1234649986]). As part of the award, Manhattan Bio will receive a one-year residency at JLABS @ NYC, including laboratory space, access to equipment, and connection to the global Johnson & Johnson Innovation network of experts.
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The QuickFire Challenges are designed to accelerate game-changing, early-stage innovations in the pharmaceutical and medical device sectors. With unique biologic platforms focusing on RNA degraders (RNADs) and antibody-drug conjugates (ADCs), Manhattan Bio is building a pipeline of medicines targeting selective vulnerabilities to treat cancers and other diseases. Manhattan Bio’s lead program, MABS-139, is a rationally designed RNA-degrading protein which exhibits broad anti-tumor efficacy in preclinical animal models and successfully completed Phase 1 dose-escalation study, yielding promising results. Additional programs being developed via internal R&D efforts and in collaboration with the National Cancer Institute and Binghamton University include ADCs utilizing proprietary tumor-cleavable linker-payload chemistries for targeted delivery of next-generation warheads to the tumor cells.
"We are very excited to be selected for QuickFire Challenge award," said Dr. Borys Shor, CEO of Manhattan Bio. "The network and resources available to us will be valuable as we continue to build out a broad pipeline of protein- and antibody-based therapeutics and accelerate progress toward the clinic. We greatly appreciate this recognition of our talented team’s dedication to advancing breakthrough innovations for patients"