Innate Pharma and Sanofi collaborate on next generation antibody-drug conjugates using Innate’s site-specific conjugation technology

On April 16, 2015 Innate Pharma reported that it has entered into a collaboration agreement with Sanofi to apply Innate Pharma’s site-specific conjugation technology to the development of new Antibody Drug Conjugates ("ADC") (Press release, Innate Pharma, APR 15, 2015, View Source [SID:1234503021]).

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Hervé Brailly, CEO and co-founder of Innate Pharma, said: "We are very pleased to collaborate with Sanofi, a global healthcare leader. By combining some of Sanofi R&D’s anti-tumor antibodies with our novel technology for conjugating cytotoxic compounds, this collaboration opens the gate to next-generation ADCs with a potentially improved therapeutic index for patients with cancer".

Sanofi-Aventis Recherche & Développement, the French R&D affiliate of Sanofi, will evaluate site-specific payload conjugation to enhance ADC pharmacokinetics, efficacy and safety and has the option to enter into a licencing agreement with Innate Pharma on this technology. Other terms of the agreement are undisclosed.