On November 3, 2021 Inhibrx, Inc. (Nasdaq: INBX), a biotechnology company with four clinical programs in development and an emerging pre-clinical pipeline, reported that the Company will be presenting three poster presentations at the Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper)’s (SITC) (Free SITC Whitepaper) annual meeting, to be held in Washington, D.C. and in a virtual platform, on November 10-14, 2021 (Press release, Inhibrx, NOV 3, 2021, View Source [SID1234594290]).
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"We are excited to share some of the preclinical data related to our clinical candidates, INBRX-105 and INBRX-106, which inform the selection of pharmacodynamic biomarkers, dosing and clinical strategy," said Brendan Eckelman, Ph.D., Inhibrx Co-founder and Chief Scientific Officer.
"Additionally, we will be introducing the first emerging pipeline candidate from our targeted cytokine platform, INBRX-121, which specifically expands and enhances the cytotoxic capacity of NK cells."
Poster Presentation Details:
Title: INBRX-106: A novel hexavalent anti-OX40 agonist for the treatment of solid tumors
Lead Author: Emily Rowell, Ph.D.
Category: Novel Single-Agent Immunotherapies
Abstract: 856
Session Date & Time: ePoster on display beginning Friday, November 12th; 7:00 a.m. EST
Title: INBRX-105- Key pharmacokinetic and pharmacodynamic parameters that correlate with the anti-tumor activity of a bispecific PD-L1 conditional 4-1BB agonist
Lead Author: Heather Kinkead, Ph.D.
Category: Biomarkers, Immune Monitoring, and Novel Technologies
Abstract: 12
Session Date & Time: Saturday, November 13th; 7:00 a.m.- 8:30 p.m. EST
Title: INBRX-121 is an NKp46-targeted detuned IL-2 with antitumor activity as a monotherapy or in combination with multiple cancer immunotherapy modalities
Lead Author: Florian J. Sulzmaier, Ph.D.
Category: Immune-Stimulants and Immune Modulators
Abstract: 722
Session Date & Time: Saturday, November 13th; 7:00 a.m.- 8:30 p.m. EST
The scientific posters will be accessible through the following link on the investors section of Inhibrx’s website at View Source