On November 1, 2023 Immunocore Holdings plc (Nasdaq: IMCR), a commercial-stage biotechnology company pioneering the development of a novel class of T cell receptor (TCR) bispecific immunotherapies designed to treat a broad range of diseases, including cancer, infectious diseases and autoimmune conditions, reported that it will present data for KIMMTRAK (tebentafusp-tebn) in metastatic uveal melanoma and cutaneous melanoma at the Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper)’s (SITC) (Free SITC Whitepaper) Annual Meeting (1st – 5th November) and the Society for Melanoma Research (SMR) Congress (6th – 9th November) (Press release, Immunocore, NOV 1, 2023, View Source [SID1234636639]).
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Across the two scientific conferences, the company will present seven posters:
Presentation and poster details
Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper)
Title: Molecular features associated with long survival on tebentafusp in previously untreated metastatic uveal melanoma in a phase 3 trial (abstract #30)
Presenting author: Marlana Orloff
Session: Poster Hall, Saturday November 4, 2023
Title: Novel regulators of ImmTAC-mediated killing of melanoma cancer cells revealed by genome-wide CRISPR-Cas9 screens (abstract #1108)
Presenting author: Aleksandra Raczka
Session: Poster Hall, Saturday November 4, 2023
Society for Melanoma Research
Title: Propensity score analysis of the effect of corticosteroids on survival from tebentafusp in metastatic uveal melanoma (mUM) (poster #P-096)
Presenting author: Alexandra Ikeguchi
Session: Poster display, Monday November 6, 2023 – Wednesday November 8, 2023
Title: Tumor microenvironment (TME) features and serum cytokines in patients with metastatic uveal and cutaneous melanoma treated with tebentafusp (poster #P-225)
Presenting author: Omid Hamid
Session: Poster display, Monday November 6, 2023 – Wednesday November 8, 2023
Title: A Phase 2/3 trial in progress on tebentafusp as monotherapy and in combination with pembrolizumab in HLA-A*02:01+ patients with previously treated advanced non-uveal melanoma (TEBE-AM) (poster #P-047)
Presenting author: Diwakar Davar
Session: Poster display, Monday November 6, 2023 – Wednesday November 8, 2023
Title: Evidence of tumor response in orbital lesions treated with tebentafusp in metastatic uveal melanoma patients (poster #P-089)
Presenting author: Marcus Butler
Session: Poster display, Monday November 6, 2023 – Wednesday November 8, 2023
Title: Early ctDNA reduction is associated with better overall survival in the Ph 3 trial of tebentafusp in previously untreated metastatic uveal melanoma (poster #P-163)
Presenting author: Ryan Sullivan
Session: Poster display, Monday November 6, 2023 – Wednesday November 8, 2023