On June 1, 2021 Halozyme Therapeutics, Inc. (NASDAQ: HALO) reported abstracts and presentations by its collaborators for the 2021 American Society of Clinical Oncology (ASCO) (Free ASCO Whitepaper) Annual Meeting, which will be held June 4-8, 2021 (Press release, Halozyme, JUN 1, 2021, View Source [SID1234583360]).
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Janssen Research & Development, LLC (Janssen)-sponsored study with therapeutics utilizing ENHANZE technology:
Subcutaneous daratumumab in combination with bortezomib, cyclophosphamide, and dexamethasone (VCd) in patients with newly diagnosed light chain (AL) amyloidosis
Oral abstract session: Updated results from the Phase 3 ANDROMEDA study of DARZALEX FASPRO in combination with bortezomib, cyclophosphamide and dexamethasone (D-VCd) for the treatment of newly diagnosed AL amyloidosis (Abstract #8003).
Bristol Myers Squibb-sponsored study with therapeutics utilizing ENHANZE technology:
CheckMate 8KX: Phase 1/2 multi-tumor preliminary analyses of a subcutaneous formulation of nivolumab (± rHuPH20)
Poster session: The first data on the pharmacokinetics (PK), safety, tolerability, and pharmacodynamics (PD) of subcutaneous nivolumab + rHuPH20 (Abstract #2575).
Roche-sponsored study with therapeutics utilizing ENHANZE technology:
Potential non-drug cost differences associated with the use of the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection (PH FDC SC) in the treatment of HER2-positive early breast cancer patients in Western Europe and the United States
Poster session: The aim of this study is to estimate the incremental difference in non-drug costs between PH FDC SC and PT IV for a typical patient receiving treatment for HER2-positive early breast cancer in Western Europe and the United States (Abstract #544).