On April 24, 2019 EpimAb Biotherapeutics, an emerging biopharmaceutical company based in Shanghai, reported that the United States Patent and Trademark Office (USPTO) has granted the U.S. Patent No. 10,266,608 entitled "Fabs-In-Tandem Immunoglobulin and Uses Thereof" (Press release, EpimAb Biotherapeutics, APR 24, 2019, View Source [SID1234535333]). Based on EpimAb’s globally filed first application, this patent broadly covers bispecific antibodies obtained utilizing the company’s FIT-Ig technology in a composition of matter claim.

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"This patent underscores the novelty of EpimAb’s approach in bispecific antibody generation and forms an important foundation of EpimAb’s growing IP portfolio," said Dr. Chengbin Wu, Founder and CEO of EpimAb Biotherapeutics. "The first granted patent in a major pharmaceutical market like the US therefore represents a significant milestone for EpimAb and takes us another step towards our goal to become a leading innovator in cancer biologics."

EpimAb is developing multiple programs based on its FIT-Ig platform for the treatment of various cancers. Its most advanced product candidate EMB-01, a cMet/EGFR bispecific with a novel mechanism of action was discovered and rapidly developed to the clinic by EpimAb. It is currently being investigated in a clinical Phase I/II trial in the USA and China. A second FIT-Ig molecule is currently under preclinical development with further molecules following soon, rapidly growing EpimAb’s pipeline of bispecific antibodies.