On August 9, 2010 Cancer Research Technology Ltd (‘CRT’) – Cancer Research UK’s commercialisation and development arm, and Scancell Holdings Plc, (AIM:SCLP), the developer of therapeutic cancer vaccines – reported that they have signed an agreement under which Scancell has been granted a licence to use a human antibody known as 105AD7 (Press release, Cancer Research Technology, AUG 9, 2010, View Source [SID1234523335]).

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105AD7 is a human monoclonal antibody that mimics the complement regulatory protein, CD55. The antibody was discovered and originally developed at the University of Nottingham with support from Cancer Research UK and has previously been evaluated in clinical trials for osteosarcoma. The agreement will give Scancell a worldwide licence to use 105AD7 for the development of new ImmunoBody vaccines for any immunotherapy indication.

The licence will be restricted to the use of the antibody as a framework for future ImmunoBody vaccines. Scancell’s current ImmunoBody vaccines, such as SCIB1, its vaccine currently in Phase I clinical trials for the treatment of melanoma, use a deimmunised* antibody as the framework. 105AD7 will allow Scancell to use a fully human framework for the development of future ImmunoBody vaccines.

Under the terms of the agreement, Scancell will make an upfront payment to CRT in addition to development milestone payments, and royalty payments on future sales. Scancell will exclusively fund the development work, and have sub-licensing rights on agreed terms.

Professor Lindy Durrant, Chief Executive Officer of Scancell, commented:
"I am pleased that we have secured this important agreement with Cancer Research Technology. By utilising antibody 105AD7, Scancell will be able to further enhance the clinical utility and safety of Scancell’s ImmunoBody platform both in cancer and other immunotherapy indications."

Dr Phil L’Huillier, Cancer Research Technology’s director of business management, said:
"Through this deal with Scancell we are able to take forward this antibody arising from research from our worldclass scientists into commercial development to potentially make new vaccines to treat a range of diseases."

(Filing 10-Q , Exelixis, AUG 5, 2010, View Source [SID:1234501029])

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Cancer, cervical
It is in a Phase I/II tumor specific vaccination therapy for advanced/recurrent cervical cancer using HLA-A*2402 restricted specific epitope peptides cocktail derived from tumor genome/tumor related angiogenetic factors genome (Clinical trial, Trial ID:UMIN000003902, UMIN, JUL 11, 2010, View Source [SID1234520547]). Advanced/recurrent cervical cancer with the conditions of unremoval by surgery, or refractory, chemo-resistant disease. Objective I: To elcidate the feasibility and efficacy of HLA-A*2402 restricted Specific Epitope Peptides Cocktail of FOXM1,MELK,and HJURP. Objective 2: Safety,Efficacy

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On July 7, 2010 Cancer Research Technology (CRT)* and Medical Research Council Technology (MRCT)** reported it will ‘swap’ medical discoveries to accelerate the translation of early scientific research into patient benefit (Press release, Cancer Research Technology, JUL 7, 2010, View Source [SID1234523336]).

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CRT and MRCT can offer each other rights to manage, develop and license discoveries from research funded by parent charity Cancer Research UK and the government’s Medical Research Council. The arrangement will explore ways to make the most of each organisation’s expertise and speed up the licensing of potential products for patient benefit.

CRT can offer MRCT the opportunity to manage, develop and license certain intellectual property *** outside the field of cancer. And in return MRCT can offer CRT the opportunity to manage, develop and license certain intellectual property **** with an application in cancer.

Dr Keith Blundy, CEO Cancer Research Technology said: "This is in effect a two-way skills transplant between two organisations with expertise in different areas of medical research.

"It’s a win-win-win – for CRT, for MRCT and also for patients. CRT has a solid expertise in forming global networks with industry partners to turn cancer discoveries into exciting ways to treat cancer with aim to increase survival.

"In return the arrangement lets us hand over discoveries from our researchers that fall outside of cancer to the technology transfer leaders in specific disease research fields.

"Both organisations can contribute their skills and knowledge to bring the maximum patient benefit across a range of diseases as efficiently and quickly as possible."

Dave Tapolczay, CEO of MRC Technology, said: "The strengthening of this partnership is of strategic importance. The arrangement will allow both MRC Technology and Cancer Research Technology to use their core strengths to maximise translation of discovery to benefit public health. We are confident this arrangement will speed up delivery of life-changing healthcare treatments and bring further value and strength to UK science."

Both CRT and MRCT will share revenue resulting from the arrangement – agreed on a case by case basis.

Dr Keith Blundy, CEO Cancer Research Technology added: "As well as each organisation providing management commercialisation skills, each will use drug discovery expertise to translate drug targets into commercial opportunities

"This is an enormously important arrangement which will save both organisations and industry money and time and achieve our common goals of increasing survival from a wide range of diseases."

On July 6, 2010 BioMS Medical Corp. (TSX: MS) reported it has changed its name to Medwell Capital Corp. ("Medwell" or "the Company") (Press release, BioMS Medical, JUL 6, 2010, View Source [SID:1234510643]). Shares of Medwell will continue trading on the Toronto Stock Exchange under the symbol ‘MS’ until the end of the trading on July 7, 2010. On Thursday, July 8, 2010, Medwell will begin trading under the new symbol ‘MWC’.

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The name change was approved by shareholders at the Company’s annual meeting held on June 25, 2010.

About Medwell Capital Corp.

Medwell Capital Corp. is a Canadian-based service provider in the healthcare industry. For further information please visit www.medwellcapital.com.

This press release may contain forward-looking statements, which reflect the Company’s current expectation regarding future events. These forward-looking statements involve risks and uncertainties that may cause actual results, events or developments to be materially different from any future results, events or developments expressed or implied by such forward-looking statements. Such factors include, but are not limited to, changing market conditions, the successful and timely completion of clinical studies, the establishment of corporate alliances, the impact of competitive products and pricing, new product development, uncertainties related to the regulatory approval process and other risks detailed from time to time in the Corporation’s ongoing quarterly and annual reporting. We undertake no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.