Prometic to report its third quarter 2018 financial results and hold conference call / webcast

On November 12, 2018 Prometic Life Sciences Inc. (TSX: PLI) (OTCQX: PFSCF) ("Prometic") reported that it will report its financial results for the third quarter ended September 30, 2018 on Wednesday November 14, 2018 after market close (Press release, ProMetic Life Sciences, NOV 12, 2018, https://resources.prometic.com/latest-content/prometic-to-report-its-third-quarter-2018-financial-results-and-hold-conference-call-webcast [SID1234531241]).

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Prometic will host a conference call at 11:00am (ET) on Thursday November 15, 2018. The telephone numbers to access the conference call are 1-888-231-8191 and 647-427-7450. An audio replay of the call will be available as of Thursday November 15, 2018 at 2:00pm (ET). The numbers to access the audio replay are 416-849-0833 and 1-855-859-2056 using the following password (1190238).

Coherus BioSciences Management to Present at the 27th Annual Credit Suisse Healthcare Conference

On November 12, 2018 Coherus BioSciences, Inc. (Nasdaq: CHRS), reported that senior management will be presenting at the 27th Annual Credit Suisse Healthcare Conference being held in Scottsdale, Arizona on Thursday, November 15 at 9:45 am MST (Press release, Coherus Biosciences, NOV 12, 2018, View Source [SID1234531698]).

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The audio portion of the presentation will be available on the investors page of the Coherus BioSciences website at View Source

FDA Grants Fast Track Designation to ONC201 for the Treatment of Adult Recurrent H3 K27M-mutant High-Grade Glioma

On November 12, 2018 Oncoceutics, Inc., a clinical-stage drug discovery and development company with a novel class of compounds that selectively target G protein-coupled receptors for oncology reported that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to Oncoceutics’ investigational cancer drug ONC201 for the treatment of adult recurrent H3 K27M-mutant high-grade glioma (Press release, Oncoceutics, NOV 12, 2018, View Source [SID1234558364]).

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The FDA’s Fast Track designation is intended to facilitate the development of new therapies for serious or life-threatening diseases or conditions and with the potential to address unmet medical needs for such diseases or conditions. A company with an investigational medicine receiving Fast Track designation may be eligible for more frequent communications with the FDA and may receive an expedited review of the new drug application.

"It is exciting to see a therapeutic option emerge from translational research into a formal clinical development program for a devastating disease such as H3 K27M high-grade glioma," said Patrick Y. Wen, MD, Director of the Center For Neuro-Oncology at Dana-Farber Cancer Institute. "Novel therapeutic approaches are important for our recurrent midline glioma patients who currently do not have effective treatment options."

bridgebio pharma llc signs joint collaboration agreement with cincinnati children’s to accelerate development of genetic disease therapeutics

On November 12, 2018 BridgeBio Pharma LLC and Cincinnati Children’s Hospital Medical Center reported they are entering into a research collaboration to identify and develop genetic disease therapies (Press release, BridgeBio, NOV 12, 2018, https://investor.bridgebio.com/news-releases/news-release-details/bridgebio-pharma-llc-signs-joint-collaboration-agreement [SID1234576271]). This partnership will combine BridgeBio’s strengths in therapeutic development for diseases of high unmet need with Cincinnati Children’s world-class researchers and clinicians. As a global research center of excellence, Cincinnati Children’s represents an ideal partner for BridgeBio and reinforces BridgeBio’s commitment to collaborating with leading researchers toward the mutual goal of discovering new therapies targeting genetic diseases at the source.

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"BridgeBio is privileged to partner with leading experts at Cincinnati Children’s, an institution whose impact on science and patients we admire. We hope we can help advance the mission by partnering to move therapies forward to patients," said Neil Kumar, co-founder and CEO of BridgeBio.

"We are excited to launch this new alliance with BridgeBio to bring new and innovative therapies to some of the most vulnerable patients impacted by rare and complex genetic diseases," said Margaret Hostetter, MD, Chief Medical Officer of Cincinnati Children’s and Director, Cincinnati Children’s Research Foundation.

"This collaboration exemplifies Cincinnati Children’s commitment to accelerating discoveries towards commercialization through win-win academic-industry partnerships," added Mike Pistone, Director of Acceleration for Cincinnati Children’s Innovation Ventures, the group managing this program.

Under the terms of the agreement, BridgeBio will have the opportunity to sponsor and collaboratively develop selected research programs. The agreement represents a flexible model that facilitates accelerated genetic disease research.

Ziopharm Oncology Announces $50 Million Private Placement

On November 12, 2018 Ziopharm Oncology, Inc. (Nasdaq: ZIOP), reported that it has entered into definitive securities purchase agreements for the sale of its common stock and warrants to purchase common stock in a private placement that is expected to result in gross proceeds to the Company of approximately $50 million, before deducting placement agent and other offering expenses (Press release, Ziopharm, NOV 12, 2018, View Source [SID1234531224]). The private placement is being led by existing stockholder, MSD Partners, L.P. Other participants include Miller Value Partners, White Rock Capital Management and Level One Partners, LLC.

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Pursuant to the terms of the securities purchase agreement, at the closing of the private placement, Ziopharm will issue and sell 18,939,394 shares of common stock and warrants to purchase up to 18,939,394 additional shares of common stock at a per unit purchase price of $2.64. The warrants will become exercisable on the date that is six months following the date of issuance, have a per share exercise price of $3.01 and will expire five years from the date of issuance. The private placement is expected to close on or about November 13, 2018, subject to the satisfaction of customary closing conditions. Additional details regarding the private placement will be included in a Form 8-K filed by Ziopharm with the Securities and Exchange Commission (the "SEC").

Neither the shares of Ziopharm common stock nor the warrants to be issued in the private placement have been registered under the Securities Act of 1933, as amended (the "Securities Act"). Accordingly, these securities may not be offered or sold in the United States except pursuant to an effective registration statement or an applicable exemption from the registration requirements of the Securities Act. Ziopharm has agreed to file a registration statement with the SEC to register the resale of Ziopharm common stock to be issued in the private placement as well as the Ziopharm common stock issuable upon exercise of the warrants.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such jurisdiction.