Johnson & Johnson to Participate in 36th Annual JP Morgan Health Care Conference

On December 19, 2017 Johnson & Johnson (NYSE: JNJ) reported that it will participate in the 36th Annual JP Morgan Health Care Conference on Monday, Jan. 8, at the Westin St. Francis in San Francisco. Alex Gorsky, Chairman and Chief Executive Officer, will represent the Company in a session scheduled at 2:30 p.m. (Pacific Time)/5:30 p.m. (Eastern Time) (Press release, Johnson & Johnson, DEC 19, 2017, View Source [SID1234522708]). A subsequent Question & Answer session is scheduled for 3:00 p.m. (Pacific Time)/6:00 p.m. (Eastern Time).

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A webcast for both events will be available to investors and other interested parties by accessing the Johnson & Johnson website at www.investor.jnj.com.

A recording of the webcasts and podcasts will be available approximately two hours after each event.

TX16 Completed PK Study

ON December 19, 2017 Tanvex rported that its recently completed pharmacokinetics (PK) study of the company’s biosimilar product candidate, TX16, showed favorable results supporting PK similarity of TX16 and the reference product, US-licensed Avastin (Press release, Tanvex BioPharma, DEC 19, 2017, View Source [SID1234524595]). In a prospective, single dose, double blinded, parallel group study conducted in 69 healthy adult male subjects, the test to reference ratio of geometric least squares (LS) mean and corresponding 90% confidence interval (CI) for the primary endpoint, AUC 0-∝, were within the acceptance range of 80.00 to 125.00%. In addition the test to reference ratios of geometric LS means and corresponding 90% CIs of the other PK endpoints, AUC 0-t and C max, were also within the acceptance range of 80.00% to 125.00% demonstrating similar peak concentrations and extent of exposure between TX16 and Avastin.

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Overall, both TX16 and Avastin were generally safe and well tolerated by the study subjects, with mild to moderate treatment-emergent adverse events and no severe or serious adverse events reported.

Avastin (bevacizumab) is a vascular endothelial growth factor-specific angiogenesis inhibitor approved in the US for the treatment of multiple indications in combination with other agents, including metastatic colorectal cancer, non-squamous non-small cell lung cancer, glioblastoma, metastatic renal cell carcinoma, cervical cancer, and recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer.

According to IMS data, US sales of Avastin were US$3.1 billion in 2016.

Myriad Genetics to Present at the 36th Annual J.P. Morgan Healthcare Conference

On December 19, 2017 Myriad Genetics, Inc. (NASDAQ:MYGN), a leader in molecular diagnostics and personalized medicine, reported that Mark C. Capone, president and CEO, is scheduled to present at the JP Morgan Annual Healthcare Conference at 2:00 p.m. PT on January 8, 2018, in San Francisco, California (Press release, Myriad Genetics, DEC 19, 2017, View Source [SID1234522709]).

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The presentation will be available to interested parties through a live audio webcast accessible through a link in the investor information section of Myriad’s website at www.myriad.com.

Saniona Spin-Out, Scandion Oncology Raises DKK 2 Million and Prepares for a Potential Public Listing

On December 19, 2017 Saniona, a leading biotech company in the field of ion channels, reported that its spin-out company, Scandion Oncology, has raised DKK 2 million in a private placement. Scandion intends to use the proceeds to develop its lead compound, SCO-101, for the treatment of chemotherapy resistant cancer and to mature the company for a potential public listing (Press release, Scandion Oncology, DEC 19, 2017, View Source;lang=en-GB&companycode=s-sanion&v= [SID1234522693]).

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Scandion Oncology raised DKK 2 million from a group of investors including member of the management and board of directors. The company expects to raise additional financing during spring 2018 either through an additional private placement or a public listing. Saniona owns 47.3% of Scandion Oncology following this initial financing round. The founders, management and the other shareholders of Scandion Oncology are independent of Saniona’s board, management and major shareholders of Saniona.

"Our clinical candidate SCO-101 represents a first-in-class treatment for chemotherapy resistant cancer, which is one of the most important challenges in modern oncology. With the successful closing of this private placement, we can now initiate the development of SCO-101 and prepare for the Phase 2a study in chemotherapy resistant cancer. In parallel, we are preparing for our next financing round and are diligently working to mature the company for a potential public listing," said Kim Arvid Nielsen, CEO of Scandion Oncology.

Jørgen Drejer, CEO of Saniona, added, "I am very pleased with the progress in our spin-out, Scandion Oncology. We believe that Scandion Oncology’s development of innovative therapies for chemotherapy resistant cancers will benefit not only cancer patients but also Saniona’s shareholders. Scandion Oncology has established the company within its own facilities and appointed an independent board of directors. Furthermore, the company has acquired a complementary asset from a third party and entered into a collaboration with Cambrex for the manufacture of GMP material for SCO-101."

Scandion Oncology was founded in May 2017 and subsequently acquired Saniona’s clinical candidate, SCO-101, which has been evaluated in Phase 1 studies for another indication. In 2015 Saniona granted scientists at the University of Copenhagen, Denmark rights to test SCO-101 and related compounds in their screening systems. This led to the discovery that certain compounds displayed the potential to overcome chemotherapy resistance by restoring the sensitivity of cancer cells toward standard chemotherapy. The parties filed a patent and formed Scandion Oncology for further development and commercialisation of this discovery. In addition to SCO-101, Scandion acquired a platform comprised of a large series of chemical analogues and associated knowledge.

For more information, please contact

Thomas Feldthus, EVP and CFO, Saniona, Mobile: +45 2210 9957, E-mail: [email protected]

Kim Arvid Nielsen, CEO, Scandion Oncology, Mobile: +45 2143 1017, E-mail: [email protected]

This information is such information as Saniona AB (publ) is obliged to make public pursuant to the EU Market Abuse Regulation. The information was submitted for publication, through the agency of the contact person set out above, at 09:45 CET on December 19, 2017.

Aviragen Therapeutics Inc. and Vaxart, Inc. Investor Presentation

On December 19, 2017 Aviragen Therapeutics Inc. and Vaxart, Inc. presented Investor Presentation (Presentation, Nabi Biopharmaceuticals, DEC 19, 2017, View Source [SID1234522710]).

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