On January 4, 2018 CureVac AG, a leading clinical-stage biopharmaceutical company focused on the development of pioneering mRNA therapeutics, and Arcturus Therapeutics Ltd. (NASDAQ:ARCT), an RNA medicines company, reported they have entered into a broad strategic collaboration to jointly discover, develop and commercialize novel messenger RNA (mRNA) therapeutics (Press release, CureVac, JAN 4, 2018, View Source [SID1234522914]).

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Under the agreement, the companies will collaborate to develop up to four molecular therapy products for rare diseases using Curevac’s optimized natural mRNA sequence (RNAoptimizer) and Arcturus’s lipid-mediated nucleic acid delivery system (LUNAR). The agreement focuses on developing mRNA therapeutics for enzyme replacement and antibody generation. Development costs will be shared between the companies, with plans to co-commercialize products in the future under a profit sharing arrangement. The first mRNA therapy to be jointly developed and potentially commercialized by the companies will target ornithine transcarbamylase (OTC) deficiency, a genetic disease characterized by the accumulation of ammonia in the blood. The collaboration also grants CureVac access to the full suite of Arcturus’s lipid-mediated delivery intellectual property to enable the development of additional mRNA product candidates.

"This collaboration for up to four products establishes a sound relationship with Arcturus, which we believe is one of the leaders in developing lipid-mediated delivery systems for mRNA molecules," said Ingmar Hoerr, Ph.D., co-founder and CEO of CureVac. "Just as important, we are excited to have secured access to Arcturus’s leading intellectual property rights for future product development in molecular therapies. This partnership combines both companies’ technology platforms with the expertise necessary to develop the next generation of therapeutics based on the considerable potential of mRNA."

"We are thrilled to combine Arcturus’s platform technologies and expertise with CureVac’s recognized capabilities in mRNA construct optimization and GMP manufacturing to co-develop messenger RNA medicines for patients in need," said Joseph Payne, President and CEO of Arcturus. "We believe our collaboration with CureVac has the potential to help reduce costs, mitigate manufacturing risks, and accelerate our timelines for ushering quality mRNA medicines into the clinic."

On January 4, 2018 SpringWorks Therapeutics, a mission-driven medicines company dedicated to developing innovative potential new treatments for underserved patient communities, reported that it will present at the 36th Annual J.P. Morgan Healthcare Conference (Press release, SpringWorks Therapeutics, JAN 4, 2018, View Source [SID1234538854]). Lara S. Sullivan, M.D., President and Founder, and Saqib Islam, Chief Financial Officer and Chief Business Officer, are scheduled to present at 1:30 p.m. PT on Tuesday, January 9, 2017 at the Westin St. Francis in San Francisco, CA.

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"Having launched SpringWorks Therapeutics only four months ago, we are honored to have been selected to present at the J.P. Morgan Healthcare Conference," stated Mr. Islam. "Our collaborative, patient-centric business model is providing innovative ways to advance promising, investigational therapies that may be otherwise trapped on the sidelines in larger pharmaceutical and biotech companies. We look forward to sharing highlights of our novel approach and late-stage pipeline as we enter a catalyst-rich 2018."

On January 4, 2018 Myovant Sciences (NYSE: MYOV), a clinical-stage biopharmaceutical company focused on developing and commercializing innovative therapies for women’s health and endocrine diseases, reported that Lynn Seely, M.D., President and Chief Executive Officer of Myovant Sciences, will present at the 36th Annual J.P. Morgan Healthcare Conference in San Francisco, California on Wednesday January 10, 2018 at 2:30 p.m. PT (Press release, Myovant Sciences, JAN 4, 2018, http://investors.myovant.com/news-releases/2018/01-04-2018-133105307 [SID1234522891]).

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The event will be webcast live and may be accessed via the Events page under the Investors and Media section of Myovant’s website at www.myovant.com. Please connect to the company’s website at least 15 minutes prior to the presentation to ensure adequate time for any software download that may be required to listen to the webcast. A replay will also be available at the same location for 30 days following the conference.

On January 4, 2018 Syros Pharmaceuticals (NASDAQ: SYRS), a biopharmaceutical company pioneering the development of medicines to control the expression of genes, reported that its Chief Executive Officer, Nancy Simonian, M.D., will present a corporate overview, including 2018 objectives, at the 36th Annual J.P. Morgan Healthcare Conference (Press release, Syros Pharmaceuticals, JAN 4, 2018, View Source [SID1234522895]). Details are as follows:

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36th Annual J.P. Morgan Healthcare Conference
Date: Thursday, January 11
Time: 10:30 a.m. PST (1:30 p.m. EST)
Location: Westin St. Francis Hotel, 335 Powell St., San Francisco, CA

The presentation will be followed by a question and answer session.

A live webcast of the presentation and question and answer session will be available on the Investors & Media section of the Syros website at www.syros.com. An archived replay of the webcast will be available for approximately 30 days following the presentation.

On January 4, 2018 Aveo Presented Corporate Presentation Slide Deck dated January 2018 (Presentation, AVEO, JAN 4, 2018, View Source [SID1234522920]).

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