On March 6, 2018 Kura Oncology, Inc. (Nasdaq:KURA), a clinical-stage biopharmaceutical company focused on the development of precision medicines for oncology, reported its participation in the Cowen and Company 38th Annual Health Care Conference. Troy Wilson, Ph.D., J.D., President and Chief Executive Officer, is scheduled to present an overview of the company on Tuesday, March 13, 2018 at 8:40 a.m. ET / 5:40 a.m. PT (Press release, Kura Oncology, MAR 6, 2018, http://ir.kuraoncology.com/news-releases/news-release-details/kura-oncology-present-cowen-and-company-38th-annual-health-care [SID1234524453]). The conference will be held from March 12-14, 2018 in Boston.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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A live audio webcast of the presentation will be available in the Investors section of Kura Oncology’s website at www.kuraoncology.com, with an archived replay available for 30 days following the event.

On March 6, 2018 Five Prime Therapeutics, Inc. (Nasdaq: FPRX), a biotechnology company discovering and developing innovative immuno-oncology protein therapeutics, reported that Aron Knickerbocker, Chief Executive Officer, will present at the Cowen and Company 38th Annual Health Care Conference, March 12, 2018, at 11:20 am ET (Press release, Five Prime Therapeutics, MAR 6, 2018, http://investor.fiveprime.com/news-releases/news-release-details/five-prime-therapeutics-present-cowen-and-company-38th-annual [SID1234524645]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The presentation will be webcast and may be accessed at the "Events & Presentations" section of the Company’s website at View Source Five Prime will maintain an archived replay of the webcast on its website for 30 days after the conference.

On March 6, 2018 Atara Biotherapeutics, Inc. (Nasdaq:ATRA), a leading off-the-shelf T-cell immunotherapy company developing novel treatments for patients with cancer, autoimmune and viral diseases, reported that Isaac Ciechanover, M.D., the Company’s President and Chief Executive Officer, will present at the Cowen and Company 38th Annual Health Care Conference on Tuesday, March 13, 2018 at 8:00 a.m. EDT (Press release, Atara Biotherapeutics, MAR 6, 2018, http://investors.atarabio.com/news-releases/news-release-details/atara-biotherapeutics-present-cowen-and-company-38th-annual [SID1234524435]). The conference will be held at the Boston Marriott Copley Place Hotel in Boston, MA.

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Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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A live audio webcast of the presentation will be available by visiting the Investors section of the Atara website at www.atarabio.com. An archived replay of the webcast will be available on the Company’s website for 14 days following the presentation.

on March 6, 2018 Loxo Oncology, Inc. (Nasdaq:LOXO), a biopharmaceutical company innovating the development of highly selective medicines for patients with genetically defined cancers, reported that Joshua H. Bilenker, M.D., chief executive officer, will present a corporate overview at the Cowen and Company 38th Annual Health Care Conference in Boston on Tuesday, March 13, 2018 at 10:00 a.m. ET (Press release, Loxo Oncology, MAR 6, 2018, View Source [SID1234524454]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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A live broadcast of the presentation will be available at View Source An archived replay of the presentation will be available on the company’s website for 30 days following the presentation.

On March 6, 2018 Apexigen, Inc., a clinical-stage biopharmaceutical company, and the Pediatric Brain Tumor Consortium (PBTC), reported a clinical trial collaboration to evaluate Apexigen’s APX005M, an investigational immune activating compound that targets CD40, in pediatric patients with recurrent or refractory brain tumors (Press release, Apexigen, MAR 6, 2018, View Source [SID1234591002]). CD40 is an immune co-stimulatory receptor essential to the activation of both innate and adaptive immune responses against cancer. There is an unmet need in pediatric oncology for effective treatments for Central Nervous System (CNS) tumors. Immunotherapy is currently considered a promising area of investigation in clinical oncology and it is expected that novel immune-activating agents such as APX005M will provide additional benefit to complement the currently used immune checkpoint inhibitors.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The PBTC will conduct a Phase 1 dose escalation trial of APX005M in children at its participating academic medical centers and children’s hospitals across the United States. Objectives of the study include establishing the safety, tolerability, pharmacokinetics and preliminary evidence of activity for APX005M in the pediatric population. Ira Dunkel, M.D., Chairman of the PBTC Steering Committee, said, "We believe that CD40 activation is a very promising area of immunotherapy for cancer, and we are happy to be collaborating with Apexigen to evaluate APX005M in our pediatric patients."

"In a Phase 1 study, APX005M has demonstrated immune stimulation in adult patients with solid tumors," said Xiaodong Yang, M.D., Ph.D., President and CEO of Apexigen. "We are excited about the opportunity to collaborate with the PBTC to explore the effects of treatment with APX005M in this underserved pediatric population."

APX005M is a novel, humanized investigational monoclonal antibody designed to overcome the systemic immune suppression that typically affects cancer patients through activation of CD40, a co-stimulatory receptor on the antigen presenting cells that is essential for activating both innate and adaptive immunity.