10-K/A [Amend] – Annual report [Section 13 and 15(d), not S-K Item 405]

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Triumvira Immunologics to Present at Two Upcoming Conferences:

On April 30, 2018 Triumvira Immunologics, Inc., a privately held biopharmaceutical company developing a novel platform for engineering T cells to attack multiple types of cancers, reported that it will present an abstract at the International Society for Cellular Therapy Annual Meeting (ISCT) in Montreal, and a company overview at the Bloom Burton & Co. Healthcare Investor Conference in Toronto, both on Thursday, May 3 (Press release, Triumvira Immunologics, APR 30, 2018, View Source [SID1234525860]).

At the ISCT, Dr. Chris Helsen, Director of Platform Development, will be presenting during the "Cancer Immunotherapy" breakout plenary on May 3, 11:00am – 12:15pm ET. The abstract is titled T cells engineered with T-Cell Antigen Coupler (TAC) receptors display robust efficacy against solid and liquid tumor xenografts in the absence of any toxicity.

At the Bloom Burton & Co. conference, President and Chief Executive Officer Dr. Paul Lammers will provide an overview of Triumvira and the improvements the company is making over current therapies with its novel immuno-oncology platform T Cell-Antigen Coupler (TAC). Dr. Lammers will also be giving updates on Triumvira’s lead drug, CD19-TAC01, which is targeted to enter clinical development in Q1 2019 for the treatment of patients with CD19 positive B-cell malignancies. Dr. Lammers will be presenting May 3, at 3:00pm ET and will be available for private meetings during the day.

About the ISCT
The International Society of Cellular Therapy is a global society of clinicians, regulators, technologists, and industry partners with a shared vision to translate cellular therapy into safe and effective therapies to improve patients’ lives. ISCT Members gain access to an influential global community of peers, experts, and organizations invested in cell therapy. ISCT offers a unique collaboration between academia, regulatory bodies, and industry partners in cell therapy translation.

About the Bloom Burton & Co. Conference
The Bloom Burton & Co. Healthcare Investor Conference brings together U.S., Canadian and international investors who are interested in the latest developments in the Canadian healthcare sector. Attendees will have an opportunity to obtain corporate updates from the premier Canadian publicly traded and private companies through presentation and private meetings.

10-K/A [Amend] – Annual report [Section 13 and 15(d), not S-K Item 405]

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Altum Pharmaceuticals, Inc. completes acquisition of Lexi Pharma Inc, and its pipeline of novel therapies for bone disease and oncology

On April 30, 2018 Altum Pharmaceuticals Inc. ("Altum" or "Altum Pharmaceuticals") reported that it has completed the acquisition of Lexi Pharma Inc. ("Lexi Pharma"), a Canadian pharmaceutical company focused on the development of AP-002, a new chemical entity (NCE) small molecule with an active US FDA IND (Investigational New Drug application) (Press release, Altum Pharmaceuticals, APR 30, 2018, View Source [SID1234598056]). AP-002, is a novel molecule, that selectively targets bone resorption while also demonstrating anti-tumor activity. Preclinical studies have shown that AP-002 selectively inhibits osteoclast differentiation and bone resorption with a novel mechanism of action distinct from other anti-bone resorption agents.

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The acquisition provides Altum with an enhanced pipeline by adding potential therapies for bone and oncology disorders, as well as, the addition of a world class management team. Lexi Pharma team members have collectively filed 15 New Drug Applications (NDAs) and have been involved in the development and launch of successfully marketed products including: Byetta, Bydureon, Camptosar, Dacogen, Ellence, Emcyt, Erbitux, Folotyn, Panretin, Symlin, Sutent, Targretin, Vidaza, Velcade, and Zarnestra.

"We are delighted to have the Lexi team join us at Altum to help us realize the goal of addressing unmet needs for women’s health with novel therapeutic approaches. As part of the merger, we are thrilled to have experienced and motivated female C-level executives joining Altum to help implement our novel strategies," said Altum Pharmaceuticals’ Chief Executive Officer, Dr. Ahmad Doroudian. "The merger represents another important step in the execution of our strategy to become a global player in women’s health."

As part of the Altum’s merger with Lexi Pharma:

Ali Ardakani, the Chief Executive Officer of Lexi Pharma, will join Altum’s board.
Dr. Angela Ogden, will join Altum as the new Chief Medical Officer.
Dr. Gina Stetsko will join Altum as the new Chief Development Officer.
Dr. Hooshmand Sheshbaradaran, will join Altum as Chief Operating Officer.
Lexi Pharma’s Chief Medical Officer Dr. Angela Ogden said, "We are excited to become part of Altum Pharmaceuticals. Our combined pipeline allows us to focus on specific therapeutic needs of women, such as, HPV and bone disorders. Our experienced and cohesive development team looks forward to bringing new treatment paradigms to women around the world."

Xencor to Host First Quarter 2018 Financial Results Webcast and Conference Call on May 7, 2018

On April 30, 2018 Xencor, Inc. (NASDAQ: XNCR), a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of autoimmune diseases, asthma and allergic diseases and cancer, reported that it will release first quarter 2018 financial results after the market closes on Monday, May 7, 2018 (Press release, Xencor, APR 30, 2018, View Source [SID1234525863]). Xencor management will host a webcast and conference call the same day at 4:30 p.m. ET (1:30 p.m. PT) to discuss the financial results and provide a corporate update.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The live call may be accessed by dialing (877) 359-9508 for domestic callers or (224) 357-2393 for international callers, and referencing conference ID number 5056978. A live webcast of the conference call will be available under "Events & Presentations" in the Investors section of the Company’s website located at www.xencor.com. The webcast will be archived on the company website for 90 days.