On August 26, 2018 Harbour BioMed reported that it has completed a Series B round financing of $85 million to accelerate the growth of its innovative therapeutic pipeline, including both clinical and discovery stage programs (Press release, Harbour BioMed, AUG 26, 2018, View Source [SID1234529067]). GIC Private Limited, Singapore’s sovereign wealth fund, led the financing round, with participation from new investors, including China Life Private Equity Investment Company and Vertex Ventures, and Series A investors AdvanTech and Legend Capital

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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"During the one and half years since we established operations, Harbour has successfully expanded its network of collaborations for its core transgenic mouse technologies, rapidly built an innovative pipeline through internal discovery and in-licensed development stage programs in the areas of oncology and immunology, and established an experienced and professional team," said Dr. Jingsong Wang, the Founder, Chairman and CEO of Harbour BioMed. "The financing is a very strong vote of confidence by our new and existing investors in our vision for the company, strategy, progress to date and our team. With their continued support, we will accelerate the growth and advancement of our pipeline through both internal innovation and external collaboration."

Harbour BioMed was established in December 2016 around a Series A round of $50 million and the acquisition of the Netherlands-based fully human transgenic antibody technology company, Harbour Antibodies BV and its subsidiaries. The company has integrated the Harbour Mice technologies into its newly built antibody technology and discovery biology, preclinical and clinical development operations, entered into multiple license and collaboration agreements for its Harbour Mice, and established an innovative therapeutic pipeline based on internal discovery and in licensing activities. In early 2018 Harbour raised an A+ Round from CDH and AdvanTech to support its in-licensed clinical programs for Greater China. Harbour’s development programs include:

An anti-FcRn based antibody against multiple autoimmune diseases, including myasthenia gravis and neuromyelitis optica, and a biologic against inflammatory dry-eye disease, among other potential indications. Harbour, which in-licensed these assets in 2017, is developing them for the Greater China market. Harbour recently filed two INDs for three different indications in China to conduct clinical trials with these assets.
A CD3-based bi-specific antibody therapy against Her-2 overexpressed cancer in clinical development, acquired in August 2018, which Harbour is developing for the Greater China market.
A clinical stage, anti-PD-L1 antibody for the treatment of multiple solid tumors and hematological cancers, acquired in August 2018, that Harbour is developing worldwide outside of China.

On August 24, 2018 Kiadis Pharma N.V. ("Kiadis Pharma" or the "Company") (Euronext Amsterdam and Brussels: KDS), a clinical stage biopharmaceutical company developing a T-cell immunotherapy product candidate designed to reduce Graft versus Host Disease (GVHD) and relapse after hematopoietic stem cell transplantations (HSCT), reported that it will be announcing Financial Results for the six months ended June 30, 2018 at 7:00am CEST on Friday, August 31, 2018 (Press release, Kiadis, AUG 24, 2018, View Source [SID1234529064]).

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Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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For more information, please contact:

Kiadis Pharma:

Karl Hård, Head of IR & Communications
Tel. +31 611 096 298
[email protected]

Optimum Strategic Communications:

Mary Clark, Supriya Mathur, Hollie Vile
Tel: +44 203 714 1787
[email protected]

On August 24, 2018 Kiadis Pharma N.V. ("Kiadis Pharma" or the "Company") (Euronext Amsterdam and Brussels: KDS), a clinical stage biopharmaceutical company developing a T-cell immunotherapy product candidate designed to reduce Graft versus Host Disease (GVHD) and relapse after hematopoietic stem cell transplantations (HSCT), reported that it will be announcing Financial Results for the six months ended June 30, 2018 at 7:00am CEST on Friday, August 31, 2018 (Press release, Kiadis, AUG 24, 2018, View Source [SID1234529064]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

For more information, please contact:

Kiadis Pharma:

Karl Hård, Head of IR & Communications
Tel. +31 611 096 298
[email protected]

Optimum Strategic Communications:

Mary Clark, Supriya Mathur, Hollie Vile
Tel: +44 203 714 1787
[email protected]

On August 24, 2018 Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) reported that it will webcast its management presentation at the Morgan Stanley 16th Annual Global Healthcare Conference at 9:55 a.m. Eastern Time on Wednesday, September 12, 2018 (Press release, Regeneron, AUG 24, 2018, View Source [SID1234529070]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The session may be accessed from the "Investors & Media" page of Regeneron’s website at View Source A replay of the webcast will be archived on the Company’s website and will be available for 30 days.

On August 24, 2018 Beijing Percans Oncology Co., Ltd. reported that released a blockbuster new product, a new generation of tumor cell culture products based on conditional reprogramming [1] (CR ) technology, aiming to developing customized " In Vitro Detection Kit for i-CR Primary Tumor Cell Culture " for enterprises, hospitals, and scientific research institutions (Press release, Cothera Bioscience, AUG 24, 2018, View Source [SID1234618855]). This new testing product can performdirect tumor cell drug susceptibility testing, and the results are more intuitive and can help discover new effective cancer drugs.

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Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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CR cell culture technology

For a long time, culturing tissue cells in vitro and constructing pre-clinical models have been important methods in biomedical reseearch. Cell models can help scientists not only with better understandings of molecular mechanisms and causes of diseases, but also in drug discovery and the development of new therapies. CR (Conditional Reprogramming) technology is the only proven system in the field that can cultivate normal and diseased cells without restriction, while retaining the genotype and phenotype of thecells.The method can preserve the full characteristics of cancer cells, which is critical for the construction of tumor models.

Breaking through technical barriers – i-CR tumor cell culture system

In the past two years, Percans Oncology has completed two rounds of financing, which has accelerated its development in the field of cancer detection. Improved on CR technology, Percans Oncology’s innovation goes a step further. With the ability to control which type of cells, tumorous or normal, are being cultivated, the technology can effectively eliminate the signal noise generated by normal cells, therefore greatly improving the testing accuracy and efficiency.

After extensive gathering of opinions and suggestions fromnumerous clinicians and medical research experts, and accumulating huge amount of stability test data, Percans Oncology has strived to build an accurate "i-CR primary tumor cell culture" detection system to help with customers’need for efficient and affordable research projects, including construction of primary tumor cell banks,performing accurate pharmacological analysis and efficacy testing for individualized therapies and carrying out novel oncological studies.

"i-CR Tumor Primary Cell Culture Detection Kit" uses standardized laboratory consumables and simplifies the operating procedures (from the preservation of tumor tissues to the preparation, isolation, culture of primary tumor cells, and the final quantitative detection method), which in turn helps to ensure the consistency of test results. In addition, the "i-CR Tumor Primary Cell Culture Detection Kit" will continue to expand the analysis menu and improve detection performance to broadly cover the needs of more cancer types.