On November 7, 2018 Synlogic, Inc. (Nasdaq: SYBX), reported that the Company will release its third quarter 2018 financial results after the market closes on Tuesday, November 13, 2018 (Press release, Synlogic, NOV 7, 2018, View Source [SID1234530949]). The press release will be followed by a conference call at 5:00 p.m. ET, which will be open to the public via telephone and webcast. During the conference call, the Company will review its financial results and provide a corporate update.

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The conference call dial-in numbers are (844) 815-2882 for domestic callers and (213) 660-0926 for international callers. The conference ID number for the call is 2674209. Participants may access the live webcast via a link on the Synlogic website in the Events Calendar of the Investors and Media section

On November 7, 2018 Exicure, Inc. (OTCQB:XCUR), the pioneer in gene regulatory and immunotherapeutic drugs utilizing three-dimensional spherical nucleic acid (SNA) constructs, reported plans to attend two investor conferences and two scientific conferences in November 2018 (Press release, Exicure, NOV 7, 2018, View Source;p=RssLanding&cat=news&id=2375799 [SID1234530970]).

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Exicure will be providing a corporate update November 13th, from 3:30 to 4:10 EST at the Stifel Healthcare Conference at the Lotte New York Palace, New York City. A live audio webcast will be available on the Events & Presentations section of Exicure’s website: www.exicuretx.com. A replay will be available for approximately 30 days. The company will also be attending the Jefferies London Healthcare Conference, November 14-15 at the Waldorf Hilton, London.

On November 9th and 10th the company will be presenting at the Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper) conference at the Walter E. Washington Convention Center; Washington, D.C. Additionally, the company will be presenting at the EORTC-NCI-AACR (Free EORTC-NCI-AACR Whitepaper) (ENA) Molecular Targets and Cancer Therapeutics Symposium November 13-16 at The Convention Centre Dublin; Dublin, Ireland

On November 7, 2018 Lixte Biotechnology Holdings, Inc. (OTCQB: LIXT) reported that the FDA approved its IND to conduct a Phase 1b/2 trial of the safety and therapeutic benefit of Lixte’s lead clinical compound, LB-100, in patients with low and intermediate-1 risk myelodysplastic syndrome (MDS) who have failed or are intolerant of standard treatment. The study will be conducted at Moffitt Cancer Center, Tampa, FL (Press release, Lixte Biotechnology, NOV 7, 2018, View Source [SID1234530996]).

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Dr. John S. Kovach, founder and CEO of Lixte, said, "We are very pleased to receive approval to proceed with a study of the potential benefit of our lead protein phosphatase 2A inhibitor, LB-100, in the treatment of refractory MDS to be conducted by the team at Moffitt, long-time leaders in this field. Low and intermediate-1 risk MDS are often characterized by failure to produce normal amounts of red blood cells, so that patients with this syndrome require frequent blood transfusions. Reduction in the number of transfusions needed by these patients is one major goal of therapy, and provides a readily assessable parameter of therapeutic benefit within a few months of initiating treatment. At present, there is only one drug, Revlimid (Celgene), approved for one subtype of MDS."

On November 7, 2018 Bausch Health Companies Inc. (NYSE/TSX: BHC) reported that Joseph C. Papa, chairman and chief executive officer, and Arthur J. Shannon, senior vice president and head of Investor Relations and Communications, are scheduled to participate at the Stifel 2018 Healthcare Conference in New York on Nov. 14, 2018 at 11:00 a.m. ET (Press release, Valeant, NOV 7, 2018, View Source [SID1234531177]).

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A live webcast and audio archive of the event will be available on the Investor Relations page of the Bausch Health Companies Inc. web site at: View Source

On November 6, 2018 Personalis, Inc., a provider of advanced genomic sequencing and analytics for immuno-oncology, reported that the company, along with one of their collaborators, Dr. Sekwon Jang of the Inova Cancer Center, will present new data at the upcoming Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper)’s (SITC) (Free SITC Whitepaper) 33rd Annual Meeting, taking place in Washington, D.C., November 9-11, 2018 (Press release, Personalis, NOV 6, 2018, View Source [SID1234530767]).

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Following is a list of abstracts that will be presented at the meeting.

Rapid Oral Abstracts

Session ID Title & Presenter Day & Time Location
Rapid Oral Abstracts Molecular profiling of anti-PD-1 treated melanoma patients reveals importance of assessing neoantigen burden and tumor escape mechanisms for clinical treatment
Presenter: Sekwon Jang, MD
Director, Melanoma and Cutaneous Oncology Therapeutics and Research
Inova Melanoma and Skin Cancer Center

November 9:
1:40 PM

Poster section
12
Scientific Poster Presentations

Poster Number Title & Presenter Day & Time Location
P13

Molecular profiling of anti-PD-1 treated melanoma patients reveals importance of assessing neoantigen burden and tumor escape mechanisms for clinical treatment
Presenter: Charles W. Abbott, PhD

November 9
12:45pm-2:15pm and 6:30pm-8:00pm

Hall E
P151 Improving neoantigen identification for therapeutic and diagnostic use in immuno-oncology using mass spectrometry and machine learning
Presenter: Sean M. Boyle, PhD

November 9
12:45pm-2:15pm and 6:30pm-8:00pm

Hall E
P78 More sensitive identification of T-cell receptor beta rearrangements with an augmented transcriptome method
Presenter: Eric Levy, PhD

November 10
12:20pm-1:50pm and 7:00pm-8:30pm

Hall E
Personalis will also be exhibiting during the conference (Booth #617). Representatives will be available to answer questions about the company’s cancer immunogenomics services.