ANNOUNCEMENT- PRINCIPAL FINANCIAL DATA OF FOSUN HIGH TECHNOLOGY FOR THE NINE MONTHS ENDED 30 SEPTEMBER 2018

On October 30, 2018 Shanghai Fosun High Technology (Group) Co., Ltd. ("Fosun High Technology"), a subsidiary of Fosun International Limited (the "Company"), which has issued medium-term notes in February 2018, April 2018, July 2018 and September 2018 respectively, and super commercial paper in June 2018 in the China’s interbank bond market, published its 2018 third quarter report (the "Report") on 30 October 2018, in accordance with the relevant regulations in China (Press release, Fosun Pharma, OCT 30, 2018, View Source [SID1234530388]).

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The board of directors of the Company (the "Board") would like to draw the attention of its shareholders and the investment public to the following unaudited principal consolidated financial data of Fosun High Technology for the nine months ended 30 September 2018 as set out below in the Report:

Unit: Thousand Yuan Currency: RMB
As at the end of
this reporting period As at the end of last year
Increase/decrease as at
the end of this reporting
period as compared
with the end of last year
(%)
Total assets 288,748,478 236,798,051 21.94%
Equity attributable to
owners of the parent 53,614,661 50,089,794 7.04%
From the beginning of
2018 up to the end of
this reporting period
From the beginning of
last year up to the end of
the same reporting period
of last year
Increase/decrease as
compared with the
same period of last year
(%)
Revenue from operation 34,250,739 23,433,701 46.16%
Profit attributable to
owners of the parent 3,863,135 3,601,006 7.28%

Syros to Present Clinical and Preclinical Data on SY-1365 and Earlier-Stage Pipeline at EORTC-NCI-AACR Meeting

On October 30, 2018 Syros Pharmaceuticals (NASDAQ: SYRS), a leader in the development of medicines that control the expression of genes, reported that the Company will present data from the dose escalation portion of its Phase 1 trial of SY-1365, its first-in-class selective cyclin-dependent kinase 7 (CDK7) inhibitor, in advanced solid tumor patients in an oral plenary session at the 30th EORTC-NCI-AACR (Free EORTC-NCI-AACR Whitepaper) Molecular Targets and Cancer Therapeutics Symposium taking place November 13-16 in Dublin (Press release, Syros Pharmaceuticals, OCT 30, 2018, View Source [SID1234530428]). The presentation will include data on safety, pharmacokinetics and proof-of-mechanism. These data will be the first clinical data presented on a selective CDK7 inhibitor, marking a significant milestone in the development of selective CDK7 inhibitors for the treatment of cancer.

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In additional poster presentations, Syros will present new preclinical data on the mechanistic rationale for SY-1365 in combination with carboplatin in ovarian cancer; the first preclinical data on its oral CDK7 inhibitor program; and the discovery of drug targets and patient subsets from its analysis of the super-enhancer landscape in ovarian cancer.

The abstract for the oral presentation on SY-1365 will remain under embargo until the day of the presentation. The abstracts for the poster presentations are now available online on the EORTC-NCI-AACR (Free EORTC-NCI-AACR Whitepaper) conference website at View Source

Details on the oral presentation are as follows:

Presentation Title: Proof-of-Mechanism Based on Target Engagement and Modulation of Gene Expression Following Treatment with SY-1365, a First-in-Class Selective CDK7 Inhibitor in Phase 1 Patients with Advanced Cancer
Session Date & Time: Thursday, November 15, 14:30-15:45 GMT (9:30-10:45 a.m. ET)
Presentation Time: 15:30-15:45 GMT (10:30-10:45 a.m. ET)
Session Title: Plenary Session 6: Proffered Papers
Presenter: Dejan Juric, M.D., Massachusetts General Hospital
Abstract Number: 11
Location: Auditorium, The Convention Centre Dublin

Details on the poster presentations are as follows:

Presentation Title: SY-1365, a selective CDK7 inhibitor, enhances carboplatin activity in ovarian cancer cell lines and xenografts, and transcriptionally inhibits homologous recombination repair (HRR) genes
Date & Time: Tuesday, November 13, 12:00-19:00 GMT (7:00 a.m.-2:00 p.m. ET)
Session Title: Poster Session: DNA Repair Modulation
Presenter: Liv Johannessen, Ph.D., Syros
Abstract Number: 50
Location: PB-001, Exhibition Hall, The Convention Centre Dublin

Presentation Title: An oral and selective CDK7 inhibitor demonstrates substantial anti-tumor effect in breast and ovarian cancer models
Date & Time: Tuesday, November 13, from 12:00-19:00 GMT (7:00 a.m.-2:00 p.m. ET)
Session Title: Poster Session: Molecular Targeted Agents – PART 1
Presenter: Claudio Chuaqui, Ph.D., Syros
Abstract Number: 96
Location: PB-047, Exhibition Hall, The Convention Centre Dublin

Presentation Title: Super-enhancer landscapes of ovarian cancer reveal novel epigenomic subtypes and targets
Date & Time: Friday, November 16, from 10:00-14:00 GMT (5:00-9:00 a.m. ET)
Session Title: Poster Session: Molecular Targeted Agents – PART II
Presenter: Matthew Eaton, Ph.D., Syros
Abstract Number: 400
Location: PB-063, Exhibition Hall, The Convention Centre Dublin

Rigel Announces Conference Call and Webcast to Report Third Quarter 2018 Financial Results

On October 30, 2018 Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL) reported that it will report its third quarter 2018 financial results after market close on Tuesday, November 6, 2018 (Press release, Rigel, OCT 30, 2018, View Source [SID1234530447]). Rigel senior management will follow the announcement with a live conference call and webcast at 5:00pm Eastern Time (2:00pm Pacific Time) to discuss the financial results and give a company update.

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Participants can access the live conference call by dialing (855) 892-1489 (domestic) or (720) 634-2939 (international) and using the Conference ID number 1398326. The conference call will also be webcast live and can be accessed from Rigel’s website at www.rigel.com. The webcast will be archived and available for replay for 30 days after the call via the Rigel website.

NewLink Genetics to Participate in the Stifel 2018 Healthcare Conference

On October 30, 2018 NewLink Genetics Corporation (NASDAQ:NLNK), a clinical stage biopharmaceutical company focused on developing novel immuno-oncology therapeutic candidates, reported it will present at the Stifel 2018 Healthcare Conference (Press release, NewLink Genetics, OCT 30, 2018, View Source [SID1234530682]). The conference is being held on November 13 – 14 at the Lotte New York Palace Hotel in New York City, New York.

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NewLink’s management will participate in an analyst-led fireside chat Tuesday, November 13, 2018 from 11:45 AM – 12:25 PM ET and will be available for one-on-one meetings with investors who are registered to attend the conference.

A live webcast of the conference presentation will be available on the Company’s website at www.newlinkgenetics.com in the "Investors & Media" section under "Events & Presentations".

Immune Design to Report Third Quarter 2018 Financial Results and Provide Corporate Update

On October 30, 2018 Immune Design (Nasdaq: IMDZ), an immunotherapy company focused on next-generation therapies in oncology, reported that it will report third quarter 2018 financial results after the close of U.S. financial markets on Tuesday, November 6, 2018 (Press release, Immune Design, OCT 30, 2018, View Source [SID1234530353]). Immune Design management will host a webcast conference call at 1:30 p.m. Pacific Time / 4:30 p.m. Eastern Time on November 6, 2018 to discuss the financial results and provide a corporate update.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The live call may be accessed by dialing 844-266-9538 for domestic callers and 216-562-0391 for international callers. A live webcast of the call will be available online from the investor relations section of the company website at View Source and will be archived there for at least 30 days. A telephone replay of the call will be available for five days by dialing 855-859-2056 for domestic callers or 404-537-3406 for international callers and entering the conference code: 1359112.