On January 10, 2020 Biomarck Pharmaceuticals, Ltd reported that it is delighted to have been invited to present Phase 2 clinical data from its study in NSCLC and an update on the Phase 2 study in ARDS at the JPM conference (Press release, BioMarck Pharmaceuticals, JAN 10, 2020, View Source [SID1234553043]).

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These two controlled clinical studies add to the breadth of clinical data observed in over 300 patients dosed with BIO-11006 which has already shown significant effect (p=0.029) in FEV1 in patients with COPD.

The NSCLC study was controlled with carboplatin/pemetrexed (SOC) and at 3 months showed an improvement in PR, less DP and a significant (p=0.02) improvement in ORR compared to SOC.

The ARDS clinical study compares BIO-11006 to placebo in established ARDS patients who are on a ventilator. This study has almost completed enrollment and clinical data is expected Q1, 2020

The safety profile of BIO-11006 is very encouraging with only cough and headache occurring in <5% of patients.

About BIO-11006
BIO-11006 is a novel patented peptide that inhibits the MARCKS protein. Phosphorylation of the MARCKS protein has been shown to stimulate cell division and movement. BIO-11006 is part of a portfolio of over 100 patented compounds owned by Biomarck.