Xenetic Biosciences Announces Ticker Symbol Change to XBIO

On February 14, 2014 Xenetic Biosciences, Inc. (OTCBB:XBIO), a biopharmaceutical company focused on developing next-generation biologic drugs and novel oncology therapeutics, reported that its common stock has commenced trading under new ticker symbol "XBIO" on the OTC Bulletin Board (OTCBB). Since changing its name in January, the Company has traded on the OTCBB under the ticker symbol "GAIFD (Press release, Xenetic Biosciences, FEB 14, 2014, View Source [SID1234537822])."

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Scott Maguire, CEO of Xenetic said, "We are pleased with our new ticker, which is more shareholder friendly and better represents Xenetic. This new XBIO ticker, together with our recent announcements regarding the appointment to our Board of Directors of Dr. Tim Coté, the former Director of the U.S. Food and Drug Administration Office of Orphan Products Development, and our recent agreement with Baxter Healthcare SA, which included an upfront $10 million equity investment and $100 million in potential future cash milestones, represent a major step toward making Xenetic a significant drug development player in the U.S. markets."

Xenetic currently has a total of 146,740,691 shares of common stock issued and outstanding, taking into account the Baxter investment in January, which resulted in the issuance of an additional 10,695,187 shares of common stock.

(Filing, 10-K, , FEB 14, 2014, View Source [SID:1234502762])

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AVEO and Astellas to End Worldwide Collaboration License Agreement for Development and Commercialization of Tivozanib

On February 14, 2014 AVEO Oncology and Astellas Pharma said the companies will end their worldwide collaboration and license agreement for the development and commercialization of investigational agent tivozanib. Astellas has exercised its right to terminate the agreement signed in 2011 for strategic reasons, based on the clinical status of the three indications studied (Press release AVEO, FEB 14, 2014, View Source [SID:1234500080]). Additionally, the companies agreed to discontinue the ongoing Phase II BATON (Biomarker Assessment of Tivozanib in ONcology) study in patients with colorectal cancer (CRC). The termination of the collaboration will be effective August 11, 2014 at which time tivozanib rights will be returned to AVEO. In accordance with the collaboration and license agreement, committed development expenses will be shared equally.

(Press release, Selvita, FEB 11, 2014, View Source [SID:1234504702])

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20-F – Annual and transition report of foreign private issuers [Sections 13 or 15(d)]

Teva terminated the development of Obatoclax in 2013 (Filing 20-F, Teva, FEB 10, 2014, View Source [SID:1234500812])

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