ASH 2015: New LIM Kinase inhibitor data on AML mutations with high unmet medical need

On December 8, 2015 CELLIPSE reported that during the 57th American Society of Hematology (ASH) (Free ASH Whitepaper) Congress held in Orlando, the teams from U. of Indiana Wells Center led by Pr Kapur and Institut Albert Bonniot led by Dr Lafanechère presented the results of their work in the session dedicated to Oncogene and Tumor Suppressors in Myeloïd malignancies (Press release, CELLIPSE, DEC 8, 2015, View Source [SID:1234508500]). This new data reinforces the rationale for looking into LIM Kinase inhibition to stop downstream oncogene signaling of specific mutations of Tyrosine Kinase Receptors.

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CELLIPSE is developing selective and highly potent LIM Kinase small molecule inhibitors to bring new targeted therapies against cancer indications with poor overall prognosis and high medical need such as Acute Myeloïd Leukemia and Myeloproloferative Neoplasms.