On October 5, 2023 Artios Pharma Limited (Artios), a clinical-stage biotech company led by pioneers of DNA damage response ("DDR") drug development, reported that the Company will unveil data from the initial Phase 1 study of its ataxia telangiectasia and Rad-3 related ("ATR") kinase inhibitor ART0380 as part of a poster presentation at the European Society of Medical Oncology (ESMO) (Free ESMO Whitepaper) Congress (ESMO) (Free ESMO Whitepaper) 2023 taking place October 20 to 24, 2023 in Madrid, Spain (Press release, Artios Pharma, OCT 5, 2023, View Source [SID1234635675]).

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ART0380 is a competitive, oral, highly potent, and selective ATR inhibitor undergoing clinical evaluation as monotherapy in patients with solid tumors as well as in combination with chemotherapies in patients with molecularly selected cancers. Monotherapy data presented will include safety and tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy.

Poster presentation details:

First results from the phase I trial of the ATR inhibitor, ART0380, in advanced solid tumors

Presenter: Kathleen Moore, Stephenson Cancer Center at the University of Oklahoma, Oklahoma City, United States of America

Poster Number: 680P

Session and Location: Developmental Therapeutics, Hall 8

Presentation Date and Time: Monday, October 23 from 12 – 13 CEST