On January 19, 2022 Adimab, LLC, the global leader in the discovery and optimization of fully human monoclonal and bispecific antibodies, reported that 12 new partner programs entered clinical development in 2021, including programs by Biotheus, Dragonfly, IASO, Iconic, Innovent, Mapp Biopharmaceutical, and Surface Oncology (Press release, Adimab, 19 19, 2022, View Source [SID1234605662]). This brings the total number of Adimab partner programs that have entered the clinic to 55.
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The most advanced program from Adimab’s platform is Tyvyt (Sintilimab), currently marketed in China by Innovent and Lilly. In 2021, Innovent and Lilly filed a BLA with the FDA for approval in the United States.
There are currently six additional programs in pivotal trials.
"It’s been exciting to see so many of our partners’ programs advance into the clinic. Over the last four years alone we have seen 45 new programs enter clinical trials. In addition to the volume, the success these programs are having in the clinic is remarkable," said Guy Van Meter, Chief Business Officer of Adimab.
In 2021, Adimab partners exercised 10 commercial licenses to advance programs into development, bringing the total number of optioned programs to more than 85. Partners exercising commercial options in 2021 include Biotheus, Bristol Myers Squibb, IGM Biosciences, Immunitas Therapeutics, Mapp Biopharmaceutical, Regeneron, Sanofi, and Therini, among others.
"Our goal has always been long term value creation and alignment with our partners – we win when they win. This philosophy has focused the organization on quality and ultimately enabling clinical success for our partners. Today’s announcement highlights how well we are doing against this important metric," said Tillman Gerngross, Chief Executive Officer and Co-Founder of Adimab.