On May 15, 2024 OmniAb, Inc. (Nasdaq: OABI) reported its participation in the 20th Annual PEGS Boston – The Essential Protein & Antibody Engineering Summit underway at the Omni Hotel (Press release, OmniAb, MAY 15, 2024, View Source [SID1234643364]). Earlier today the Company presented an overview of xPloration, a high-throughput single B-cell screening platform that leverages machine learning and Artificial Intelligence (AI), in a presentation titled "Deep Screening in Harmony with Artificial Intelligence for Bispecific Antibody Discovery."
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"xPloration enables large-scale data collection of massive, diverse antibody repertoires generated utilizing the Biological Intelligence built into our proprietary engineered animals, and facilitates efficient evaluation of AI selections from these repertoires," said Bob Chen, Ph.D., Senior Director, Discovery Systems. "The synergy between xPloration, OmniFlic, OmniClic, and OmniDeep enables new bispecific antibody discovery workflows for our partners. We are delighted that our innovative technology stack continues to make important impacts on partner R&D pipelines, and assists in delivering novel, highly effective therapeutic solutions to patients."
Today’s presentation included a case study demonstrating the ability to rapidly discover antibody panels from the Company’s OmniFlic and OmniClic platforms against a promising target called NKp46. These antibodies may be used by partners in a natural killer cell engager bispecific antibody. With xPloration, OmniAb’s scientific team screened tens of millions of cells and recovered thousands of unique antibody sequences. The team applied OmniDeep to help understand natural immune repertoires and to guide antibody selection and characterization, resulting in a large panel of high-affinity, potentially developable antibodies.
Dr. Chen’s presentation is available on the Scientific Publications section of OmniAb’s website.
For more information about OmniAb’s proprietary technologies, please visit www.omniab.com or contact our business development team at [email protected].