On April 16, 2024 Propanc Biopharma, Inc. (OTC Pink: PPCB) ("Propanc" or the "Company"), a biopharmaceutical company developing novel cancer treatments for patients suffering from recurring and metastatic cancer, reported that a certificate of grant for the Company’s "composition of proenzymes for cancer treatment," patent was received from the European Patent Office (Press release, Propanc, APR 16, 2024, View Source [SID1234642100]). The patent covers lower dosage ratios of the two proenzymes (trypsinogen and chymotrypsinogen) contained in the PRP formulation. This is the fourth European patent granted and after validation in selected countries across Europe, will result in the Company’s IP portfolio growing to 94 patents filed in major global jurisdictions.
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This PRP dosing patent is an important part of the IP portfolio as it covers possible future clinical dosage ranges for PRP as the Company advances into early-stage clinical development. Furthermore, Europe is considered a major global region which accounted for 23.4% of global pharmaceutical sales in 2021, according to the European Federation of Pharmaceutical Industries and Associations (EFPIA). This is a significant percentage when you consider that in 2022, the worldwide pharmaceutical market was valued at approximately $1.48 trillion by Statista.com.
"The PRP dosing patent at lower dosage ratios is an important part of our growing IP portfolio, as we seek to protect our novel invention and create future value for our shareholders," said Mr. James Nathanielsz, Propanc’s Chief Executive Officer. "We look forward to advancing PRP into the clinic, and together with our growing IP portfolio, establishing the Company as a pioneer in the way we treat this killer disease."
About PRP:
PRP is a mixture of two proenzymes, trypsinogen and chymotrypsinogen from bovine pancreas, administered by intravenous injection. A synergistic ratio of 1:6 inhibits growth of most tumor cells. Examples include pancreatic, ovarian, kidney, breast, brain, prostate, colorectal, lung, liver, uterine, and skin cancers. Orphan Drug Designation status of PRP has been granted from the US Food and Drug Administration (FDA) for treatment of pancreatic cancer.
To view the Company’s "Mechanism of Action" video on the Company’s lead asset, PRP, please click on the following link: View Source