On April 10, 2024 Bexion Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company developing a novel class of biologic therapy to treat solid tumor cancers and chemotherapy-induced peripheral neuropathy (CIPN), reported that the Company presented a poster on BXQ-350 during the American Association for Cancer Research (AACR) (Free AACR Whitepaper) Annual Meeting 2024 which took place April 5-10, 2024, in San Diego, CA. Poster details are included below (Press release, Bexion, APR 10, 2024, View Source [SID1234641976]).
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Poster Details:
Abstract Title: BXQ-350: A novel biologic that allosterically activates glucosylcerebrosidase and demonstrates signs of activity in cancer patients
Abstract Number: 3072
Poster Board Number: 12
Session Title: Signaling Pathways That Regulate Metabolism 1
Session Date: Monday Apr 8, 2024
Presenter: Gilles Tapolsky, PhD, Vice President of Pharmacology & Translational Sciences, Bexion Pharmaceuticals
The abstracts were posted to the AACR (Free AACR Whitepaper) Online Program Planner at 4:30 PM ET on Tuesday, March 5.
About AACR (Free AACR Whitepaper)
The American Association for Cancer Research (AACR) (Free AACR Whitepaper) is the first and largest cancer research organization dedicated to accelerating the conquest of cancer. The AACR (Free AACR Whitepaper) Annual Meeting program covers the latest discoveries across the spectrum of cancer research—from population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy—and highlights the work of the best minds in research and medicine from institutions all over the world.
About BXQ-350
Bexion’s lead drug candidate is BXQ-350, a first-in-class biologic containing the multifunctional, sphingolipid activator protein, Saposin C, and a phospholipid. Clinically, two Phase 1 clinical trials, one in adults and one in pediatric DIPG patients, have demonstrated a robust safety profile for BXQ-350 with evidence of single agent activity across multiple solid tumor types. Additionally, other clinical and non-clinical data suggest BXQ-350 has activity in chemotherapy-induced peripheral neuropathy, an area of high unmet medical need in solid tumor patients treated with oxaliplatin and other chemotoxic agents.