On November 6, 2023 Evaxion Biotech A/S (NASDAQ: EVAX) ("Evaxion" or the "Company"), a clinical-stage TechBio company specializing in the development of AI-Immunology powered vaccines, reported that it is hosting an online webinar featuring Key Opinion Leader (KOL) and study’s Principal Investigator (PI), Professor Adnan Khattak (Press release, Evaxion Biotech, NOV 6, 2023, View Source [SID1234637023]). The webinar will take place on November 8 at 11:30 a.m. EST.
Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:
Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing
Schedule Your 30 min Free Demo!
In this 30-minute-long event, Professor Khattak will set the scene by introducing participants to the medical field of malignant melanoma and the need that Evaxion’s personalized cancer vaccines are trying to meet. After summarizing the promising results reported in the EVX-01 Phase 1 clinical trial, Adnan will dive into Evaxion’s latest EVX-01 Phase 2 clinical update and how these appear to confirm the benefits previously observed for this innovative immunotherapy. In the end, a Q&A session will be held for anyone who wants to learn more about this study and its underlying technology.
Evaxion’s Chief Executive Officer, Christian Kanstrup, commented: "‘This latest clinical update stands as a testament to Evaxion’s unwavering dedication to transforming patients’ lives through innovative and targeted immunotherapies. Despite initial skepticism surrounding our pioneering work in personalized cancer vaccines, we are now reaping consistently positive outcomes that we believe hold the promise to change the lives of melanoma patients." Reflecting on how these results may impact the oncology field in the near future, Christian added, "‘We firmly believe that our AI-Immunology platform has the potential to spearhead a revolution in immuno-oncology, extending far beyond melanoma and positively touching the lives of countless individuals."
To learn more about the clinical impact of Evaxion’s innovative EVX-01 vaccine and gain understanding of how personalized cancer vaccines can revolutionize the field of immuno-oncology, please register by following this link.
About EVX-01 Phase 1 Clinical Trial
The open-label, single-arm, single-center Phase 1 study was conducted in collaboration with DTU, SSI, the Center for Genomic Medicine at Rigshospitalet, and CCIT-DK. The study aimed to assess the safety and efficacy of the EVX-01 vaccine in combination with anti-PD1 (pembrolizumab or Nivolumab) in patients with metastatic melanoma. The design consisted of multiple 15-27mer peptides comprising one or more patient-specific neoantigens formulated with the novel liposomal adjuvant CAF09b to potentiate immune responses. The primary objective was to evaluate the safety and tolerability of the combination of EVX-01 and a checkpoint inhibitor. Additional information can be accessed under clinical trial ID NCT03715985.
About EVX-01 Phase 2 Clinical Trial
EVX-01 is Evaxion’s lead clinical asset and constitutes a peptide-based personalized cancer vaccine. The Phase 2 clinical study is a self-sponsored open-label, single-arm, multi-center trial carried out in collaboration with Merck Sharp & Dohme LLC, and together with leading principal investigators and research centers from Italy and Australia aims at evaluating the efficacy and safety of EVX-01 vaccination in combination with anti-PD1 treatment (pembrolizumab) in treatment-naive patients with metastatic or unresectable malignant stage III or IV melanoma. More information can be accessed under clinical trial ID NCT05309421.