On August 17, 2023 Kintara Therapeutics, Inc. (Nasdaq: KTRA) ("Kintara" or the "Company"), a biopharmaceutical company focused on the development of new solid tumor cancer therapies, reported that it will host a virtual KOL event on VAL-083, a potential first-in-class small molecule chemotherapeutic for glioblastoma, on Monday, August 21, 2023 at 11:00 AM ET (Press release, Kintara Therapeutics, AUG 17, 2023, View Source [SID1234634475]). To register for the event, click here.
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The event will feature Patrick Y. Wen, M.D. (Harvard Medical School) and John de Groot, M.D. (UCSF Health) who will discuss the current treatment landscape for patients suffering from glioblastoma (GBM), the most common and lethal form of brain cancer, along with Kintara’s potential treatment solution with VAL-083, a potential first-in-class small molecule chemotherapeutic.
Kintara is currently advancing VAL-083 in the GBM AGILE Study, which is an international registrational Phase II/III clinical study for GBM, with top-line data before the end of calendar 2023. VAL-083 has completed two open-label, biomarker-driven, Phase II studies in MGMT-unmethylated GBM. MGMT is a DNA-repair enzyme that is associated with resistance to temozolomide, the current standard-of-care chemotherapy used in the treatment of GBM.
A live question and answer session will follow the formal presentations. A replay will be available after the call at the link here.
ABOUT PATRICK Y WEN, M.D.
Patrick Y Wen, M.D. is a Professor of Neurology at Harvard Medical School, and Director of the Center for Neuro-Oncology at Dana-Farber Cancer Institute in Boston, MA. Dr. Wen serves as Co-PI of the National Cancer Institute supported Adult Brain Tumor Consortium, and member of the Steering Committee of the Response Assessment in Neuro-Oncology (RANO) Working Group. Dr. Wen graduated from the Medical College of St. Bartholomew’s Hospital, University of London. He completed his internal medicine training at the University of London ‘s postgraduate hospitals and his neurology residency in the Harvard-Longwood Neurology Training Program. His research is focused on novel treatments of brain tumors, especially targeted molecular agents. His other clinical interests include neurologic complications of cancer. Dr. Wen has authored or co-authored hundreds of peer-reviewed articles that have been published in journals such as Neurology, Neuro-Oncology, Current Opinion in Neurology, and Journal of Clinical Oncology. He serves as President of the Society for Neuro-Oncology and SNO Executive Editor of Neuro-Oncology.
ABOUT JOHN DE GROOT, M.D.
John de Groot, M.D. is a neuro-oncologist who specializes in diagnosing and managing the care of patients with primary brain and spine tumors (those at the site where disease began, as compared with tumors that result from the disease spreading). Dr. de Groot has brought new therapies from the laboratory into the clinic to treat patients with brain cancer. In particular, he has contributed to the development of glioblastoma treatments. He has a special interest in using blood analyses, imaging studies and other indirect biomarkers (measurable elements that may indicate disease) to evaluate the efficacy of novel therapies. In one study, he is looking at ways to overcome physiological limitations in drug delivery to brain tumors, such as through focused ultrasound. He regularly advises and collaborates with other researchers on promising therapies under development. Dr. de Groot earned his medical degree from the University of Texas Medical Branch at Galveston. He completed a residency in neurology at Johns Hopkins University and a fellowship in neuro-oncology at the University of Texas MD Anderson Cancer Center.