On June 23, 2023 Sonnet BioTherapeutics Holdings, Inc. (NASDAQ:SONN) ("Sonnet" or the "Company"), a biopharmaceutical company developing innovative targeted biologic drugs, reported that John Cini, PhD, Chief Scientific Officer and Co-Founder, and Richard Kenney, MD, Chief Medical Officer, will be featured speakers at the 4th Annual Cytokine-Based Drug Development Summit in Boston, Massachusetts, June 27-29 (Press release, Sonnet BioTherapeutics, JUN 23, 2023, View Source [SID1234632876]).

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Presentation details:
June 27, 1:00 – 4:00 pm
John Cini will co-lead a workshop entitled, "Examining Cytokine Biology to Develop a Specific &
Effective Drug"

June 29, 2:40 – 3:10 pm
Richard Kenney will deliver a talk entitled, "A Tale of Two Forms of IL-12: The Benefits of Extending PK"

CIPN Study (SB211) Preliminary Update
In the SB211 study, patients are being randomized to one of three treatment groups that receive 20 µg SON-080, 60 µg SON-080, or a matching placebo in a blinded fashion, three times a week for 12 weeks. As of June 22, 2023, seven patients have been enrolled. While the groups remain blinded, doses have been tolerated well with some mild-to-moderate transient injection site reactions. As the protocol requires a total of nine patients to be dosed for at least two weeks before a safety review by the Data Safety Monitoring Board (DSMB), we expect the DSMB to meet during the third quarter of 2023. Following the completion of the DSMB review, we anticipate announcing the initial safety data.