On June 21, 2023 Ozette Technologies, Inc., a technology-driven life sciences company, reported its collaboration with Umoja Biopharma, Inc., a transformative immuno-oncology company creating off-the-shelf treatments for solid and hematologic cancers (Press release, Umoja Biopharma, JUN 21, 2023, View Source [SID1234632837]). Umoja will use Ozette’s AI-powered single-cell technology for their preclinical studies.
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As part of this work, the Ozette Platform will be used to provide research and development (R&D) support and evaluate biomarker endpoints from preclinical tumor-bearing, humanized mouse models. Humanized mouse models are often deployed in preclinical studies as a tool for modeling human immune responses in the evaluation of potential therapeutics and treatment effects before first-in-human studies. The goal of this collaboration is to help derive insights that have the potential to catalyze Umoja’s therapeutic program development.
"Our mission is to unlock the power of the immune system using computation and machine learning. As a result, we can quickly understand how the immune system is evolving and what that means for a therapy and a patient at the single-cell level," said Dr. Ali Ansary, CEO and Co-founder of Ozette. "This collaboration with Umoja is an important opportunity to continue showcasing Ozette’s technology and innovative impact on the vast variety of therapeutic indications, including cutting-edge T-cell treatments."
Umoja and Ozette share a common mission to increase the efficiency of drug development and expand access to transformative immunotherapies through technology innovation. The partnership will leverage Ozette Endpoints and Ozette Discovery to enable both companies’ multidisciplinary scientific and bioinformatic teams to collaborate and expand the benefits of CAR T-cell immunotherapy to patients in need.
"Our collaboration with Ozette is the next step in expanding the value of our preclinical data by leveraging their advanced single-cell technology," said Ryan Larson, Ph.D., Senior Vice President of Translational Science at Umoja. "The Ozette Platform will allow us to efficiently distill complex biology, that traditionally relies on manual analysis, into actionable insights rapidly. Together, we’re able to gather a deeper and wider set of preclinical insights from our data which, in turn, allows us to increase the efficiency of developing our transformative therapeutics. We’re excited to expand our R&D efforts with Ozette on broader applications at Umoja."