The children’s cancer therapy development institute announces creation of Artisan Biopharma

On September 17, 2019 The Children’s Cancer Therapy Development Institute (cc-TDI) reported the creation of Artisan Biopharma (artisanbio.com), a Public Benefit Corporation pediatric cancer biopharmaceutical company, wholly owned by the 501c3 nonprofit, cc-TDI (Press release, Children’s Cancer Therapy Development Institute, SEP 17, 2019, View Source [SID1234631990]).

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Artisan Biopharma (EIN 84-3079359) is a newly formed, angel-funded for-profit benefit corporation wholly-owned by the 501(c)3 nonprofit, cc-TDI. Our mission is to create a quiet cultural revolution in the way new drugs are brought to market for pediatric cancers. We incorporated September 17, 2019, and we are currently engaged with tax and security counsel to finalize our operational structure with respect to the nonprofit. Our stated mission as a public benefit corporation is to provide research and interventions related to the prevention and treatment of cancer in children.

Target market: Orphan drug indications in pediatric cancers
Few rare cancer patient populations with unmet clinical need are as vulnerable and in need of advocacy as children with cancer. Pharmaceutical companies have historically faced significant financial disincentives to pursue pediatric oncology therapeutics, including low incidence, high costs of conducting pediatric trials, and a lack of funding for early-stage research. We are leveraging the deep preclinical domain expertise of cc-TDI to more efficiently identify and in-license compounds. Our goal is to reverse the 40+ year drought represented by only 8 drug approvals for pediatric cancer. To achieve this goal, we aim to have 5 new compounds reach the clinic annually for children with high risk cancers.

Artisan advantage
The rapid advancement of new oncology drugs has created a massive, de-risked discovery tool for translational science, many of which remain novel molecular entities ready to match to rare disease indications. The founding equity investor of Artisan Biopharma, the Children’s Cancer Therapy Development Institute (cc-TDI.org), is an established partner to industry (NVS, PFE, LLY) for preclinical sciences. Artisan was formed as a natural opportunity to develop and market cancer drugs for childhood cancer, generating sustainable funding for cc-TDI’s drug discovery engine. Artisan launched with 15 pipeline candidates and a network of over 1200 families directly touched by pediatric cancer.