iBio Announces Issuance of U.S. Patent Covering AI-Engineered Epitope Discovery Engine

On January 5, 2023 iBio, Inc. (NYSEA:IBIO) ("iBio" or the "Company"), an AI-driven innovator of precision antibody immunotherapies, reported that the United States Patent and Trademark Office has issued U.S. Patent No. 11,545,238, entitled "Machine Learning Method For Protein Modelling To Design Engineered Peptides," which covers a machine learning model developed to design engineered epitopes which allow precise steering of therapeutic antibodies towards specific regions of a target protein (Press release, iBioPharma, JAN 5, 2023, https://ir.ibioinc.com/news-events/press-releases/detail/201/ibio-announces-issuance-of-u-s-patent-covering [SID1234625897]).

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"We are thrilled to be issued this U.S. patent, which solidifies our position as a leader in AI-driven drug discovery, and whose claims guarantee broad coverage of our proprietary, epitope-steering antibody discovery engine," said Martin Brenner, DVM. Ph.D., iBio’s Chief Scientific Officer. "In addition to marking an important milestone as we transform iBio into an AI-powered biotech company, this patent provides us with a competitive advantage as we continue to build our differentiated pipeline, with benefits that extend to our potential future partners."

iBio’s RubrYc Discovery Engine is designed to tackle complex and challenging drug targets with the goal of developing safer and more effective immunotherapies for difficult-to-treat cancers. It uses a combination of a proprietary epitope steering technology, a specialized antibody library, and AI-powered antibody optimization to quickly identify and optimize molecules that can effectively address challenging drug targets. This allows for faster discovery compared to traditional antibody discovery methods.