On June 2, 2022 Median Technologies (ALMDT) reported that it will be presenting an abstract at the 2022 ASCO (Free ASCO Whitepaper) Annual Meeting, June 3-7, McCormick Place, Chicago, IL, USA (exhibition dates: June 4-6) (Press release, MEDIAN Technologies, JUN 2, 2022, View Source [SID1234615456]).
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Details of the session include:
Abstract # / Poster # – The adjudication rates between readers in Blinded Independent Central Review (BICR) of advanced esophageal cancer trials with or without immune checkpoint initiators as first-line therapy
Session: Gastrointestinal Cancer, Gastroesophageal, Pancreatic and Hepatobiliary
Date: Saturday June 4, 2022
Time: 8:00 AM – 11:00 AM CDT
Place: McCormick Place South, Hall A, Poster Board 27
The study analyzed a pool of advanced esophageal cancer trials with or without immune checkpoint inhibitors, which used RECIST 1.1, and documented the proportion of reader discrepancies, reader performance through monitoring procedures. 4 esophageal cancer BICR trials that included 1,875 patients (8,501 time-points) involving 14 radiologists were analyzed. Trials had an average adjudication rate of 45.28%. The discordances of baseline lesion selection (34.4% of discordances) and lesion measurement (40.3% of discordance) in follow up visits are the main reasons triggering adjudications in esophageal cancer central reading. Appropriate reader training and monitoring are solutions which can not only mitigate a large portion of the commonly encountered reading errors, but also help to reach more consensus on lesion selection and measurement between readers.
The Median’s clinical team will be available at booth #2098, Exhibit Hall A to discuss the abstract results from June 4 to June 6, 9:00 am-5:00 pm.
The ASCO (Free ASCO Whitepaper) Annual Meeting is the world’s premier oncology conference, organized by the American Society of Clinical Oncology (ASCO) (Free ASCO Whitepaper), the largest oncology society in the world. Each year, the ASCO (Free ASCO Whitepaper) conference brings together more than 35,000 oncologists from all around the globe, and is attended by all medical, educational and industrial stakeholders involved in the field of oncology worldwide. More about the ASCO (Free ASCO Whitepaper) Annual Meeting: View Source