On November 2, 2021 OncoSec Medical Incorporated (NASDAQ: ONCS) reported that it will host a conference call and webcast for investors and analysts on Friday, November 12 at 7:00 AM ET featuring key opinion leaders (KOLs) Matteo Carlino, MD, from Westmead and Blacktown Hospitals, Adil Daud, MD, from University of California San Francisco, Pablo Fernandez Peñas MD, PhD, FACD, from The University of Sydney, and Montaser Shaheen, MD, from the University of Arizona Cancer Center. The KOLs will discuss the clinical relevance of the updated KEYNOTE-695 data being presented in a poster at the SITC (Free SITC Whitepaper) 2021 Annual Meeting. Specifically, the KEYNOTE-695 clinical trial enrolled metastatic melanoma patients that are refractory to Immune Checkpoint Blockade, non-responders as defined by the Society of Immunotherapy of Cancer (SITC) (Free SITC Whitepaper) recommendations.1
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Adil Daud, M.D., a Professor of Medicine at The University of California, San Francisco, Director of the Melanoma Clinical Research, remarked, "TAVO works by optimizing cellular uptake of DNA-based IL-12 in the tumor microenvironment, leading to local, sustained production of IL-12 in the tumor, where it matters. TAVO recruits and primes immune cancer-fighting cells in the tumor leading to systemic immune responses without systemic toxicity, and we look forward to the updated data at SITC (Free SITC Whitepaper) 2021 in this highly refractory patient population."
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1Kluger HM, Tawbi HA, Ascierto ML, et al. Defining tumor resistance to PD-1 pathway blockade: recommendations from the first meeting of the SITC (Free SITC Whitepaper) Immunotherapy Resistance Taskforce. Journal for ImmunoTherapy of Cancer 2020;8:e000398. doi:10.1136/ jitc-2019-000398