Nkarta to Present Preclinical Data from Engineered NK Cell Platform at SITC 36th Annual Meeting

On October 1, 2021 Nkarta, Inc. (Nasdaq: NKTX), a biopharmaceutical company developing engineered natural killer (NK) cell therapies to treat cancer, reported four presentations at the upcoming Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper) 36TH Annual Meeting and Pre-Conference Programs to be held November 10-14, 2021 (Press release, Nkarta, OCT 1, 2021, View Source [SID1234590616]).

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The full abstracts are scheduled to be available on the SITC (Free SITC Whitepaper) website on November 9, 2021.

Presented jointly with CRISPR Therapeutics:

Title:
A Combined Strategy of CD70 CAR Co-expression with Membrane-bound IL-15 and CISH Knockout Results in Enhanced NK Cytotoxicity and Persistence
Abstract Number and Type:
16439, oral*
Poster Presentation Date and Time:
November 10, 2021, 2:40 p.m. ET

Title:
CISH Gene-knockout Anti-CD70-CAR NK Cells Demonstrate Potent Anti-tumor Activity Against Solid Tumor Cell Lines and Provide Partial Resistance to Tumor Microenvironment Inhibition
Abstract Number and Type:
113, poster
Poster Presentation Date and Time:
November 12, 2021, 7:00 am – 8:30 pm ET

Nkarta presentations:

Title:
Potentiating the Large-Scale Expansion and Engineering of Peripheral Blood-Derived CAR NK Cells for Off-the-Shelf Application
Abstract Number and Type:
151, poster
Poster Presentation Date and Time:
November 12, 2021, 7:00 am – 8:30 pm ET

Title:
KIR Haplotype Can Inform Donor Selection in the Production of Allogeneic Memory-Like CAR NK Cells for Clinical Application
Abstract Number and Type:
128, poster
Poster Presentation Date and Time:
November 13, 2021, 7:00 am – 8:30 pm ET

* View Source; a
pre-conference program; additional registration is required.