On July 12, 2021 ProfoundBio reported the closing of a $55+ million Series A financing round led by Lilly Asia Venture and co-led by LYFE Capital, with participation from Sequoia Capital China and Oriza (Press release, ProfoundBio, JUL 12, 2021, View Source [SID1234584798]). All investors from the Series Pre-A financing, K2VC, Gaorong Capital, and Chang’an Capital, also participated in this round of financing.
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ProfoundBio will use the proceeds to accelerate development and implementation of novel technology platforms for ADCs and IO therapeutics and to advance a portfolio of differentiated therapeutics into clinical development.
"We made significant progress with our lead programs and novel technology platforms since the completion of Series Pre-A financing. The additional funding will allow us to further strengthen and expand our integrated R&D capability, grow and broaden our innovative product pipeline, and prepare for multiple IND submissions in 2022 and beyond," said Baiteng Zhao, PhD, co-founder, CEO, and Chair of the Board of ProfoundBio. "We are really excited about the enthusiastic participation of the new investors and the continued support from our shareholders. I am confident that by working together, we can bring more innovative targeted therapeutics to patients with cancer sooner."
"We believe emerging modalities, such as ADCs, will bring hope to patients with solid tumor to address the significant unmet medical needs," said Dr. Fei Chen, Managing Partner of LAV. "ProfoundBio’s founding team are industry veterans with rich experience, deep knowhow and a FDA drug approval track record established during their tenure at the global leader of ADC drug development. It is a great pleasure to partner with ProfoundBio at this critical moment, and we are committed to support the company to realize the potential of ADC and create new targeted drugs for patients around the world."
According to LYFE Capital, "The antibody-drug conjugate modality has demonstrated great potential in oncology treatment. The ProfoundBio team has extensive R&D and clinical translation experience in ADC drug development. The company quickly established a strong R&D and translational platform and built up a differentiated ADC drug pipeline. We believe that the ProfoundBio team will leverage their rich experiences and efficient R&D platform to develop more differentiated ADC drug pipeline to address large unmet clinical needs in oncology."
"Congratulations to ProfoundBio on completing Series A funding!" said Lynn Yang, Partner of Sequoia Capital China. "Healthcare has been a key sector of investment since Sequoia Capital China’s establishment. We are impressed by ProfoundBio’s long-term commitment to ADC development, where the company has gained extensive experience and achieved remarkable progress. We hope ProfoundBio will continue creating value for society by helping more patients in their recovery."
"Antibody-drug conjugate (ADC) has become another important sector after monoclonal antibodies," said Yunfei Chen, Investment Director of Oriza. "ProfoundBio’s management team comes from SeaGen, a global leader in the ADC industry, which makes them well experienced in ADC development. ProfoundBio focuses on clinical unmet needs instead of overcrowded targets and mainly develops ADC drugs with innovative targets. We expect ProfoundBio to become a leading ADC enterprise. Oriza is pleased to help ProfoundBio grow rapidly and benefit more patients as soon as possible with greater success."