On August 25, 2020 Diaprost reported that it has signed an exclusive license agreement with Memorial Sloan Kettering Cancer Center for IP related to the use of PSA antibodies for therapeutic and diagnostic purposes for prostate cancer (Press release, Diaprost, AUG 25, 2020, View Source,ten%20pharmaceutical%20companies%20within%20oncology. [SID1234563994]). Diaprost is a private pharmaceutical research and development company based in Lund, Sweden and whose principle asset is h5A10, targeting PSA, a validated clinical biomarker. The h5A10 antibody combined with the appropriate payload offers the potential for highly specific therapeutic and diagnostic products, for example as a therapeutic product to deliver cytotoxic radionuclides. Diaprost’s h5A10 is already in pre-clinical development for the treatment of prostate cancer, the most common cancer in men and having a high unmet medical need. h5A10 displays high levels of specificity and affinity to PSA as well as successful tissue biodistribution and cellular internalization.

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"We believe this License Agreement complements the current IP-portfolio on the antibody h5A10 maximizing the potential of both Diaprost and the h5A10 program," said Johan Drott, the CEO of Diaprost. "We will now focus Diaprost’s efforts to deliver yet another important new oncology therapy to patients."

This h5A10 project follows in the footsteps of Diaprost’s successful earlier work in prostate cancer focusing on the hK2 antibody which led to a sale of the asset to a leading global oncology company.