On March 23, 2020 NeoImmuneTech, Inc., a clinical-stage T cell-focused biopharmaceutical company reported it has entered into an exclusive license agreement with Ubix Therapeutics, Inc. (UBIX) to develop up to three drug candidates utilizing UBIX’s Degraducer platform technology which enables target protein degradation (Press release, NeoImmuneTech, MAR 23, 2020, View Source [SID1234555768]). Under the terms of the agreement, NeoImmuneTech, Inc. (NIT) acquired the exclusive worldwide rights to research, develop, and commercialize drug candidates, in exchange for development and sales milestones, as well as royalties. The preclinical development work will be conducted in NIT’s new, state-of-the-art research institute located in the Republic of Korea.
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"We are excited to broaden our T cell-focused portfolio to include novel T cell suppressor blockades, in addition to our clinically advanced T cell amplifier, NT-I7," said Se Hwan Yang, Ph.D., President and Chief Executive Officer of NIT. "We have great confidence in UBIX’s Degraducer technology and believe this collaboration will open up new opportunities for NIT to develop multiple potent novel therapeutics for the treatment of cancers and infectious diseases with these three additional novel targets."
"We are very pleased to start this business collaboration with NIT, which has a promising clinical-stage T cell immunotherapy asset as well as an excellent management team with extensive experience in oncology drug development," said BK Seo, President and Chief Executive Officer of UBIX. "By working collaboratively with the NIT team, we are confident that the candidates we discover will be properly assessed for their potential as novel cancer immunotherapies."
About NT-I7
NT-I7 (also known as Hyleukin-7) is the only clinical-stage long-acting human IL-7 and is uniquely positioned to address unmet medical needs in immuno-oncology. IL-7 is a fundamental cytokine for naïve and memory T-cell development and for sustaining immune response to chronic antigens (as in cancer). NT-I7 exhibits a favorable PK/PD and safety profile, making it an ideal combination partner for immunotherapy standard of care (SOC) such as Checkpoint Inhibitor and CAR-T therapies. NT-I7 is being studied in multiple clinical trials in solid tumors, and being planned for testing in hematologic malignancies, additional solid tumors and other immunology-focused indications.