On December 22, 2019 Sun BioPharma, Inc. (OTCQB: SNBP), a clinical-stage biopharmaceutical company developing disruptive therapeutics for the treatment of people with pancreatic cancer, reported that an abstract describing Phase 1 clinical data for SBP-101 has been accepted for poster presentation January 24, 2020 at the American Society for Clinical Oncology (ASCO) (Free ASCO Whitepaper) 2020 Gastrointestinal Cancers Symposium, being held January 23-25 in San Francisco (Press release, Sun BioPharma, DEC 22, 2019, View Source [SID1234552611]). SBP-101 is a proprietary polyamine analogue designed to induce polyamine metabolic inhibition (PMI) a metabolic pathway of critical importance in multiple tumor types.
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Sun BioPharma also announced that Arthur J. Fratamico, RPh, MBA recently joined its Board of Directors. Mr. Fratamico is an experienced business development executive with 25 years of experience in the biopharmaceutical industry, including corporate development, commercial strategy and financing. With this addition, Sun BioPharma’s board now totals six members.
"I’m delighted to welcome Art to the Sun BioPharma board," said Michael T. Cullen, MD, MBA, CEO, President and Executive Chairman of Sun BioPharma. "Art brings highly relevant experience, and we look forward to the benefit of his expertise in business development and strategy at this significant stage of the company."
Mr. Fratamico has served as Chief Business Officer of Galera Therapeutics since January 2017. Prior to joining Galera, Mr. Fratamico served as Chief Business Officer of Vitae Pharmaceuticals until its sale to Allergan. He previously held similar executive roles with a number of biotechnology companies, including MGI Pharma and Gemin X, leading their business development efforts and facilitating the sales of both Gemin X Pharmaceuticals and MGI Pharma. He has also served in several senior marketing, product planning and new product development positions. Mr. Fratamico earned a bachelor’s degree in pharmacy from the Philadelphia College of Pharmacy and Science and an M.B.A. from Drexel University, and is a registered pharmacist.
Poster Presentation Information:
Efficacy of SBP-101, in combination with gemcitabine and nab-paclitaxel, in first-line treatment of metastatic pancreatic ductal adenocarcinoma.
Friday, January 24, 2020, 12:00 PM to 1:30 PM and 4:30 PM to 5:30 PM
Abstract 710, Board K21
Poster Session B: Hepatobiliary Cancer, Neuroendocrine/Carcinoid, Pancreatic Cancer, and Small Bowel Cancer American Society for Clinical Oncology (ASCO) (Free ASCO Whitepaper) 2020 Gastrointestinal Cancers Symposium
About SBP-101
SBP-101 is a proprietary polyamine analogue designed to induce polyamine metabolic inhibition (PMI), a metabolic pathway of critical importance in multiple tumor types. Sun BioPharma licensed SBP-101 from the University of Florida Research Foundation in 2011. The molecule has been shown to be a highly effective tumor growth inhibitor in preclinical studies of human pancreatic cancer models, demonstrating superior and complementary activity to existing FDA-approved chemotherapy agents. SBP-101 has demonstrated encouraging activity against primary and metastatic disease in clinical trials of patients with pancreatic cancer. The safety results and PMI profile demonstrated in Sun BioPharma’s previously completed first-in-human safety study provide support for evaluation of SBP-101 in combination with current standard pancreatic cancer treatment.