On December 17, 2012 Adimab reported the initiation of research collaborations with at the time an undisclosed company (later to known as Merrimack Pharmaceuticals) whereby Adimab will use its proprietary discovery platform to identify fully human antibodies against one oncology target selected by the undisclosed company (Press release Adimab, DEC 17, 2012, View Source [SID:1234500583]). The agreement gives the undisclosed company rights to commercialize antibodies generated from the collaboration. Adimab will receive upfront payments, preclinical milestones and licensing fees. In addition, Adimab is eligible to receive clinical development milestones, commercial milestones and royalties on therapeutic and diagnostic product sales.
Adimab used its proprietary yeast-based antibody discovery platform to discover fully human antibodies against human EGFR that were also cross-reactive with the murine and rhesus forms of the antigen. Adimab delivered the first panel of leads within twelve weeks of project initiation and several leads and backups were further optimized.

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